Skip to main content

Table 2 Mean absolute change of selected variables after 1 week

From: Aiming for a negative fluid balance in patients with acute lung injury and increased intra-abdominal pressure: a pilot study looking at the effects of PAL-treatment

Variable Control group PAL group p value
SOFA score    
   Respiratory 0.0 ± 1.7 -0.8 ± 1.6 0.015
   Coagulation 0.4 ± 1.1 0.1 ± 0.9 0.181
   Liver 0.3 ± 1.1 0.4 ± 0.8 0.553
   Cardiovascular -0.5 ± 1.9 -1.2 ± 2.0 0.087
   Nervous 0.2 ± 2.0 -0.2 ± 1.8 0.271
   Renal 0.2 ± 1.8 0.3 ± 1.5 0.693
   Total 0.7 ± 5.4 -1.3 ± 5.0 0.057
Number of organs failing -0.1 ± 1.6 -0.6 ± 1.5 0.115
Hemodynamic variables    
   HR (bpm) -11.5 ± 16.3 11.1 ± 95.2 0.183
   Mean arterial pressure (mmHg) 4.1 ± 13.6 0.6 ± 15.5 0.247
   CI (L/min/m2) 0.9 ± 0.2 1.0 ± 0.2 0.274
Respiratory variables    
   Plateau pressure (cmH2O) 2.2 ± 8.6 0.7 ± 8.9 0.431
   PEEP (cmH2O) 2.1 ± 3.6 0.5 ± 3.8 0.050
   Dynamic compliance (mL/cmH2O) 1.6 ± 24.3 5.3 ± 31.4 0.548
   PaO2/FIO2 ratio -12.3 ± 166.4 99.9 ± 110.5 < 0.001
EVLWI (mL/kg) -1.1 ± 3.7 -4.2 ± 5.6 0.006
Albumin (g/L) 1.1 ± 9.0 6.3 ± 8.9 0.008
Creatinine (mg/dL) -0.5 ± 2.0 -0.1 ± 1.1 0.171
Capillary leak index -17.1 ± 75.5 -31.0 ± 47.4 0.111
Intra-abdominal pressure (mmHg) 1.8 ± 3.8 -0.4 ± 3.6 0.007
Abdominal perfusion pressure (mmHg) 0.4 ± 14.4 1.3 ± 15.5 0.785
Cumulative fluid balance (mL/day) 8,027 ± 5,254 -1,451 ± 7,761 < 0.001
  1. SOFA, sepsis and organ failure assessment; HR, heart rate; CI, cardiac index; PEEP, positive end-expiratory pressure; EVLWI, extravascular lung water.