Intra-abdominal pressure and abdominal perfusion pressure in cirrhotic patients with septic shock

Annals of Intensive Care

Table 2 Outcomes of cirrhotic patients with septic shock according to the occurrence of intra-abdominal hypertension and abdominal hypoperfusion.

	IAP^a < 12 mmHg	IAP^a 1 ≥ 12 mmHg	p value	APP^a ≥ 60 mmHg	APP^a < 60 mmHg	p value
	N = 11	N = 50		N = 18	N = 43
ICU mortality, N (%)	3 (27.3)	37 (74.0)	0.005	9 (50)	31 (72.1)	0.10
Hospital mortality, N (%)	8 (72.7)	46 (92.0)	0.10	15 (83.3)	39 (90.7)	0.41
Duration of MV in days, mean ± SD	4.8 ± 7.5	8.2 ± 6.7	0.14	9.6 ± 7.1	8.9 ± 6.4	0.70
Ventilator-free days, mean ± SD	15.3 ± 11.4	4.7 ± 7.2	0.01	7.4 ± 8.7	6.3 ± 9.2	0.65
Vasopressor-free days, mean ± SD	10.5 ± 8.4	4.6 ± 7.1	0.02	8.4 ± 8.6	4.5 ± 7.1	0.07
ICU LOS (days), mean ± SD	11.1 ± 8.0	9.8 ± 6.0	0.56	11.0 ± 6.7	9.6 ± 6.2	0.45
Hospital LOS (days), mean ± SD	31.1 ± 16.8	21.1 ± 14.6	0.05	23.6 ± 10.3	22.7 ± 17.1	0.81
Requirement for RRT, N (%)	5 (45.5)	39 (78)	0.06	11 (61.1)	33 (76.7)	0.21
RRT-free days, mean ± SD	10.8 ± 12.7	5.0 ± 7.5	0.17	7.4 ± 8.9	5.5 ± 8.8	0.44

IAP ≥ 12 mmHg indicates intra-abdominal hypertension, and APP < 60 mmHg indicates abdominal hypoperfusion. IAP, intra-abdominal pressure; APP, abdominal perfusion pressure; RRT, renal replacement therapy; MV, mechanical ventilation; LOS, length of stay. ^aMean values on the first ICU day.