Annals of Intensive Care

Table 3 Restrictive versus liberal red blood cell (RBC) transfusion strategy in cardiac patients: randomized clinical trials

From: Anemia and red blood cell transfusion in critically ill cardiac patients

	Health problem	Patients	Mortality^b
First author, year^a		(n)	(95% CI)	P-value
Adults
Bracey, 1999 [73]	CABG	428	RR: 0.52 (0.13 to 2.04)	NS
Carson, 2011 [74]	Hip surgery^c	2,016	ARR: 0.9 (−1.5 to +3.4)	NS
Cooper, 2001 [52]	Myocardial infarction	46	8% versus 5%	1.0
Hajjar, 2012 [23]	Cardiac surgery	502	6% versus 5%	0.93
Hébert, 2001 [75]	ICU cardiac patients	357	22.5% versus 22.7%	1.00
Johnson, 1992 [76]	CABG	38	No difference^d	NS
Shehata, 2012 [19]	Cardiac surgery	50	16% versus 4%	NS
Pediatric cardiac surgery
Cholette, 2011 [77]	Cyanotic	60	1 death	NS
de Gast-Bakker, 2013 [78]	Non-cyanotic	107	No death	NS
Willems, 2010 [79]	Non-cyanotic	125	12.7% versus 6.5%	0.36

ARR: absolute risk reduction; CABG: coronary artery bypass graft; CI: confidence interval; RBC: red blood cell; NS: not statistically significant.
^aYear of publication.
^bRestrictive versus liberal transfusion strategy.
^cHip surgery in patients older than 50 years with atherosclerosis.
^dNo significant difference in duration or degree of exercise was demonstrated between the two groups.

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