Long-term survival and quality of life after intensive care for patients 80 years of age or older

Annals of Intensive Care

Table 3 Predictors of mortality in the ICU, in hospital, and at 1 year after admission

	ICU mortality (n = 389)	Hospital mortality for ICU survivors (n = 294)	1-year mortality for hospital survivors (n = 230)
	Adjusted HR (95 % CI)	Adjusted HR (95 % CI)	Adjusted HR (95 % CI)
Age, years	1.10 (1.03–1.18)^a
Male
Ventilator support
Mechanical ventilator support	1.99 (1.10–3.60)^a	1.40 (0.81–2.43)
Non-invasive ventilator support	0.87 (0.51–1.49)
Severity score, mean
SAPS II	1.03 (1.01–1.04)^a	1.01 (0.99–1.03)	1.01 (0.99–1.03)
Max. SOFA	1.20 (1.10–1.31)^a	1.03 (0.95–1.12)
Comorbidity
None (CCI 0)	1.00		1.00
Mild (CCI 1–2)	0.68 (0.35–1.30)		1.02 (0.43–2.46)
Moderate (CCI 3–4)	0.53 (0.25–1.11)		1.06 (0.42–2.65)
Severe (CCI ≥ 5)	0.53 (0.23–1.25)		2.09 (0.99–5.39)
Severe organ dysfunction
Respiration	1.05 (0.55–1.97)
Circulation	0.76 (0.39–1.48)
Renal	1.50 (0.88–2.54)
CNS	1.19 (0.71–1.99)
Coagulation
Liver
Admission categories
Planned surgery	1.00	1.00	1.00
Unplanned surgery	1.40 (0.54–3.65)	3.46 (1.06–11.24)^a	2.02 (0.88–4.64)
Medical reasons	2.11 (0.80–5.58)	3.17 (0.94–10.76)	1.97 (0.83–4.70)
Diagnostic groups
Respiratory failure	1.03 (0.55–1.90)		1.86 (1.13–3.07)^a
Circulatory failure
Combined respiratory and circulatory failure
Neurologic failure		1.67 (0.86–3.25)
Isolated head injury	1.56 (0.58–4.18)		9.12 (2.44–34.14)^a
Sepsis	1.20 (0.63–2.69)
Gastroenterological failure
Multiple organ failure	1.27 (0.60–2.69)	1.67 (0.64–4.31)
Multitrauma without head injury
Multitrauma with head injury	2.99 (1.04–8.60)^a
Planned surgery
Acute operation
Unspecified

ICU intensive care unit, SAPS II simplified acute physiology score II, SOFA sequential organ failure assessment, HR hazard ratio, CI confidence interval, CCI Charlson comorbidity index
^aSignificant differences