Fig. 3
From: Hyponatremia in the intensive care unit: How to avoid a Zugzwang situation?
Effects of DDAVP on PNa kinetics and urine composition and output in 20 patients admitted in the ICU for severe or profound hyponatremia: a PNa correction rate before and after DDAVP administration (n = 20). b Urine osmolarity before and after DDAVP administration (n = 14). c Urine output before and after DDAVP administration (n = 11). The box plots indicate median, interquartile ranges (25th and 75th percentiles), and minimum and maximum values. DDAVP administration allows for a marked reduction in electrolyte-free water output along with a significant reduction in the PNa correction rate. Reproduced with permission of the Clinical Journal of the American Society of Nephrology [246]