Table 3 Causes of SIADH
From: Hyponatremia in the intensive care unit: How to avoid a Zugzwang situation?
| Paraneoplastic production of AVP | Eutopic production of AVP/ enhanced hypothalamo–pituitary release of AVP |
|---|---|
| SCLC non-SCLC | CNS disorders |
| Head and neck cancer | Infectious: meningitis, encephalitis, brain abscess |
| Mesothelioma | Vascular: SAH, subdural hematoma, thrombosis |
| Stomach carcinoma | Multiple sclerosis |
| Duodenum carcinoma | Acute intermittent porphyria |
| Thymoma | Guillain-Barré syndrome |
| Lymphoma | Shy-Drager syndrome |
| Olfactory neuroblastoma | Schizophrenia |
| Bladder carcinoma | Pulmonary disorders |
| Sarcoma | Pneumonia, tuberculosis |
| Potentiation of AVP effects | Pneumothorax, atelectasis |
| Carbamazepine | Asthma, cystic fibrosis |
| Sodium valproate | Positive pressure ventilation |
| Cyclophosphamide | Drugs |
| Neuroleptics | |
| TCC, MAOI, and SSRI antidepressants | |
| Antineoplastic drugs | |
| Others | |
| Hypopituitarism | |
| Severe hypothyroidism | |
| Nausea, pain |