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Table 2 Changes in the levels of GPX, IL-6, IL-8 and IL-10 over time period in study patients

From: The effect of parenteral selenium on outcomes of mechanically ventilated patients following sepsis: a prospective randomized clinical trial

Biomarker (pg/mL)

Selenium group

Control group

P value

Glutathione peroxidase (U/mL)

 GPX on day 0

0.185 ± 0.3

0.19 ± 0.3

0.90

 GPX on day 3

0.52 ± 0.5

0.17 ± 0.2

0.02

 GPX on day 7

0.55 ± 0.5

0.24 ± 0.3

0.032

 GPX on day 10

0.62 ± 0.2

0.33 ± 0.1

0.048

 GPX on day 14

1.1 ± 1

0.89 ± 1

0.70

IL-6 (pg/mL)

 Day 0

43.3 ± 34

37.8 ± 35.6

0.61

 Day 3

25 ± 28

32.7 ± 33.3

0.42

 Day 7

21.6 ± 27.6

18.6 ± 24

0.75

 Day 10

32.5 ± 31.8

29.8 ± 33.5

0.82

 Day 14

30.9 ± 33.8

31.4 ± 30

0.97

IL-8 (pg/mL)

 Day 0

4.1 ± 5

4 ± 5.0

0.95

 Day 3

5.7 ± 7.5

4.5 ± 6.8

0.58

 Day 7

5.8 ± 8

5 ± 6.8.0

0.78

 Day 10

4.8 ± 8

5.8 ± 5

0.73

 Day 14

6.1 ± 8

6.1 ± 9

0.99

IL-10 (pg/mL)

 Day 0

4.6 ± 3

3.6 ± 2

0.26

 Day 3

4.6 ± 3.7

4.2 ± 4.5

0.76

 Day 7

3.8 ± 2.8

5.8 ± 5.7

0.21

 Day 10

3.8 ± 3.5

6.2 ± 6

0.23

 Day 14

3.9 ± 4.6

6 ± 4.6

0.26

  1. Data presented in mean ± SD
  2. GPX glutathione peroxidase, IL-6 interleukin-6, IL-8 interleukin-8, IL-10 interleukin-10