Table 2 Efficacy outcomes in study groups
Group D (DEX) | Group C (control) | p value | |
|---|---|---|---|
Diazepam consumption in 24 h, mg | 20 (20–30) | 40 (40–50) | <0.001 |
Cumulative diazepam consumption, mg | 60 (50–60) | 90 (80–100) | <0.001 |
Time of target sedation, % | 90 (90–95) | 64.5 (60–72.5) | <0.001 |
Time of insufficient sedation, % | 7.75 (5–10) | 15 (10–20) | <0.001 |
Time of oversedation, % | 2 (0–5) | 15 (10–20) | <0.001 |
Rescue sedation boluses, no. in 24 h | 1.25 (0–4) | 4 (3–6) | 0.004 |
Sedation stops, no. in 24 h | 0 (0–1) | 2 (0–3) | 0.001 |
Communication with patient | 9 (7–10) | 6 (5–6) | <0.001 |
OAA/S scale | 1 (0–2) | 2 (1–4) | 0.03 |
Haloperidol use, no. of patients (%) | 2/32 (6) | 10/32 (31) | 0.02 |
Median cumulative haloperidol dose, mg | 50 (IQR 40–55) | 60 (IQR 40–65) | 0.2 |