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Table 2 The number and percentages of total administered and interacting drugs in different drug classes

From: Important drug classes associated with potential drug–drug interactions in critically ill patients: highlights for cardiothoracic intensivists

Drug classes

Total administered drugs % (n)

D and/or X interacting drugs % (n)

D and/or X interacting precipitant drugs with E and/or G reliability % (n)

Anti-infective agents

22.35 % (398)

25.00 % (124)

45.87 % (50)

Central nervous system agents

20.50 % (365)

19.95 % (99)

14.67 % (16)

Cardiovascular drugs

19.21 % (342)

13.10 % (65)

5.50 % (6)

Gastrointestinal drugs

12.80 % (228)

6.65 % (33)

4.58 % (5)

Hormones and synthetic substitutes

6.68 % (119)

11.29 % (56)

2.75 % (3)

Respiratory tract agents

6.40 % (114)

3.22 % (16)

Electrolytic, caloric, and water balance

5.33 % (95)

6.65 % (33)

10.09 (11)

Blood formation, coagulation, and thrombosis

2.07 % (37)

3.42 % (17)

3.67 % (4)

Autonomic drugs

2.02 % (36)

3.02 % (15)

9.17 % (10)

Miscellaneous therapeutic agents

2.02 % (36)

7.05 % (35)

3.66 % (4)

Vitamins

0.56 % (10)

0.60 % (3)

Total

1780

496

109