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Table 4 Factors associated with mortality at D28

From: Influence of ICU-bed availability on ICU admission decisions

  Dead D28 N = 276 Alive D28 N = 860 Non adjusted analysis Adjusted analysis
Crude OR p Adjusted OR P
ICU
 With low refusal rate (HBA) 121 (43.8) 359 (41.7) 1 0.54 1  
 With high refusal rate (LBA) 155 (56.2) 501 (58.3) 1.09 (0.83–1.43)   1.34 (0.92–1.95) 0.12
Age (mean ± SD) 67 ± 14 55 ± 19 1.04 (1.03–1.05) <0.001   
Sex
 Male (%) 179 (65) 489 (57) 1   1  
 Female (%) 97 (35) 371 (43) 0.71 (0.54–0.95) 0.02 0.66 (0.45–0.98) 0.04
Characteristics on proposal, n (%)
 Shock 134 (48.6) 146 (17.0) 4.73 (3.51–6.37) <0.001 1.81 (1.21–2.72) 0.004
 Catecholamine infusion 82 (29.7) 66 (7.7) 5.21 (3.63–7.48) <0.001   
 Glasgow score 9.8 ± 5.0 11.9 ± 4.1 0.90 (0.87–0.93) <0.001   
 Platelets count <50,000/dl 11 (4.0) 13 (1.5) 2.94 (1.30–6.64) 0.007   
 Prothrombine time <30 % 24 (8.7) 14 (1.6) 6.17 (3.14–12.11) <0.001 2.65 (1.09–6.44) 0.03
 Creatinine level >250 µmol/l 46 (16.7) 80 (9.3) 2.19 (1.48–3.25) <0.001   
 Jaundice 14 (5.1) 22 (2.6) 2.09 (1.05–4.15) 0.03   
 Mechanical ventilation (all setting) 148 (53.6) 328 (38.1) 1.93 (1.46–2.54) <0.001   
 NIV 15 (5.4) 54 (6.3) 0.87 (0.48–1.58) 0.65   
 Oxygen administration >10L/min 67 (24.3) 147 (17.1) 1.59 (1.14–2.21) 0.006   
Preexisting diseases
 COPD 15 (5.4) 52 (6.0) 0.93 (0.51–1.68) 0.81   
 Cardiac insufficiency 22 (8.0) 34 (3.9) 2.20 (1.26–3.84) 0.005   
 Evolutive malignancy 44 (15.9) 105 (12.2) 1.42 (0.97–2.08) 0.07   
 Cirrhosis 26 (9.4) 31 (3.6) 2.89 (1.68–4.97) <0.001   
 Renal failure with ERT 8 (2.9) 20 (2.3) 1.30 (0.56–2.98) 0.54   
Mac Cabe score
 0 81 (31.4) 493 (58.4) 1   1  
 1 99 (38.4) 265 (31.4) 2.27 (1.64–3.16) <0.001 1.56 (1.02–2.37) 0.04
 2 78 (30.2) 86 (10.2) 5.52 (3.75–8.12) <0.001 3.66 (2.21–6.06) <0.001
SAPS2 62 ± 20 34 ± 16 1.08 (1.07–1.10) <0.001 1.08 (1.06–1.09) <0.001
  1. NIV non invasive ventilation, ERT extra renal therapy