Annals of Intensive Care

Table 3 Univariate and multivariate associations of PCT, CRP, SOFA score with sepsis

From: Combination of C-reactive protein, procalcitonin and sepsis-related organ failure score for the diagnosis of sepsis in critical patients

Marker	Univariate		Multivariate
Marker	OR (95 % CI)	P	OR (95 % CI)	P
Age^a	3.171 (1.833, 5.485)	<0.001	2.662 (1.382, 5.127)	0.003
Gender^a	0.470 (0.285, 0.773)	0.003	0.377 (0.203, 0.701)	0.002
WBC	0.871 (0.540, 1.405)	0.571	0.704 (0.378, 1.311)	0.268
PCT
0	1.0 (Reference)		1.0 (Reference)
1^a	4.169 (2.158, 8.055)	<0.001	3.485 (1.561, 7.780)	0.008
2	4.345 (2.155, 8.761)	<0.001	3.550 (1.467, 8.593)	0.074
3^a	8.369 (3.815, 18.359)	<0.001	6.501 (2.326, 18.173)	0.001
CRP
0	1.0 (Reference)		1.0 (Reference)
1	3.191 (1.453, 7.011)	0.004	2.491 (0.958, 6.477)	0.061
2^a	7.700 (3.138, 18.894)	<0.001	6.795 (2.188, 21.096)	0.001
3^a	8.800 (3.964, 19.537)	<0.001	6.593 (2.395, 18.125)	<0.001
SOFA	1.204 (1.117, 1.297)	<0.001	2.314 (1.260, 14.251)	0.007
IL-6
0	1.0 (Reference)		1.0 (Reference)
1	1.691 (0.586, 4.877)	0.331	1.380 (0.343, 5.559)	0.651
2	1.364 (0.468, 3.976)	0.569	0.639 (0.152, 2.678)	0.540
3	1.524 (0.526, 4.415)	0.438	0. 576 (0.146, 2.278)	0.432
4	1.227 (0.425, 3.542)	0.706	0. 422 (0.106, 1.681)	0.221

^aCox and Snell R ² was 0.282, and Nagelkerke R ² was 0.389

Back to article page