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Table 3 Cox regression model for 28-day mortality in HH

From: Outcome and features of acute kidney injury complicating hypoxic hepatitis at the medical intensive care unit

Parameter Hazard ratio (95% CI)
Unadjusted Adjusteda Adjustedb
Age 1.01 (0.99–1.02) 1.01 (0.99–1.02) 1.00 (0.99–1.02)
Gender (male) 1.22 (0.87–1.70) 1.18 (0.83–1.67) 1.26 (0.86–1.84)
Admission SOFA score 1.08 (1.04–1.12)** 1.04 (0.99–1.07) 1.03 (0.99–1.07)
Septic shock 2.07 (1.53–2.80)** 2.15 (1.32–3.50)** 2.37 (1.41–3.97)**
Cardiogenic shock 0.86 (0.64–1.17) 1.62 (0.99–2.63) 1.94 (1.16–3.24)*
INR 1.29 (1.20–1.39)** 1.24 (1.14–1.34)** 1.26 (1.13–1.39)**
Acute kidney injury (AKI)
 AKI 1 vs. no AKI 0.83 (0.33–2.11) 0.77 (0.30–1.95) 0.78 (0.30–2.00)
 AKI 2 vs. no AKI 1.69 (0.91–3.12) 1.50 (0.81–2.79) 1.55 (0.81–2.97)
 AKI 3 vs. no AKI 3.48 (2.09–5.78)** 3.40 (1.85–6.24)** 3.51 (1.86–6.62)**
Renal replacement therapy 1.86 (1.37–2.51)** 0.64 (0.42–0.97)* 0.62 (0.39–0.97)*
  1. SOFA sequential organ failure assessment, INR international normalized ratio, AKI acute kidney injury
  2. * p<0.05, ** p<0.01
  3. aPatients with chronic liver disease included—adjusted for all variables (total n= 295 )
  4. bPatients with chronic liver disease excluded—adjusted for all variables (total n = 273)