Annals of Intensive Care

Table 3 Cox regression model for 28-day mortality in HH

From: Outcome and features of acute kidney injury complicating hypoxic hepatitis at the medical intensive care unit

Parameter	Hazard ratio (95% CI)
Parameter	Unadjusted	Adjusted^a	Adjusted^b
Age	1.01 (0.99–1.02)	1.01 (0.99–1.02)	1.00 (0.99–1.02)
Gender (male)	1.22 (0.87–1.70)	1.18 (0.83–1.67)	1.26 (0.86–1.84)
Admission SOFA score	1.08 (1.04–1.12)**	1.04 (0.99–1.07)	1.03 (0.99–1.07)
Septic shock	2.07 (1.53–2.80)**	2.15 (1.32–3.50)**	2.37 (1.41–3.97)**
Cardiogenic shock	0.86 (0.64–1.17)	1.62 (0.99–2.63)	1.94 (1.16–3.24)*
INR	1.29 (1.20–1.39)**	1.24 (1.14–1.34)**	1.26 (1.13–1.39)**
Acute kidney injury (AKI)
AKI 1 vs. no AKI	0.83 (0.33–2.11)	0.77 (0.30–1.95)	0.78 (0.30–2.00)
AKI 2 vs. no AKI	1.69 (0.91–3.12)	1.50 (0.81–2.79)	1.55 (0.81–2.97)
AKI 3 vs. no AKI	3.48 (2.09–5.78)**	3.40 (1.85–6.24)**	3.51 (1.86–6.62)**
Renal replacement therapy	1.86 (1.37–2.51)**	0.64 (0.42–0.97)*	0.62 (0.39–0.97)*

SOFA sequential organ failure assessment, INR international normalized ratio, AKI acute kidney injury
* p<0.05, ** p<0.01
^aPatients with chronic liver disease included—adjusted for all variables (total n= 295 )
^bPatients with chronic liver disease excluded—adjusted for all variables (total n = 273)

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