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Table 4 Performances of 24-h urine output, 24-h urinary creatinine and urea to predict the success of an attempt of renal replacement therapy weaning

From: Daily urinary creatinine predicts the weaning of renal replacement therapy in ICU acute kidney injury patients

 

Youden index [95 % CI]

Sensitivity  % [95 % CI]

Specificity  % [95 % CI]

PPV  % [95 % CI]

NPV  % [95 % CI]

D0 urinary output (ml/24 h)

2575 [1050–3075]

38.5 [19–58]

93 [82–100]

85 [61.5–100]

62 [55–71]

D0 urinary urea (mmol/24 h)

134 [56–322]

65 [48–83]

73 [58–88.5]

68 [53–84]

70 [58–84]

D0 urinary creatinine (mmol/24 h)

4.7 [0.85–5.1]

56.5 [35–74]

96 [88.5–100]

93 [78–100]

71 [62.5–81]

D1 urinary urea (mmol/24 h)

293 [196–363]

70 [50–90]

88 [76–100]

83 [67–100]

79 [68–92]

D1 urinary creatinine (mmol/24 h)

5.15 [3.01–6.3]

75 [55–90]

88 [72–100]

84 [68–100]

82 [70–93]

D2 urinary urea (mmol/24 h)

318 [292–591]

71 [52–90]

85 [69–96]

80 [64–94]

79 [68–92]

D2 urinary creatinine (mmol/24 h)

5.56 [4.67–6.57]

86 [71–100]

81 [65–96]

78 [65–94]

88 [75–100]

  1. PPV positive predictive value, NPV negative predictive value, CI confidence interval