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Table 4 Performances of 24-h urine output, 24-h urinary creatinine and urea to predict the success of an attempt of renal replacement therapy weaning

From: Daily urinary creatinine predicts the weaning of renal replacement therapy in ICU acute kidney injury patients

  Youden index [95 % CI] Sensitivity  % [95 % CI] Specificity  % [95 % CI] PPV  % [95 % CI] NPV  % [95 % CI]
D0 urinary output (ml/24 h) 2575 [1050–3075] 38.5 [19–58] 93 [82–100] 85 [61.5–100] 62 [55–71]
D0 urinary urea (mmol/24 h) 134 [56–322] 65 [48–83] 73 [58–88.5] 68 [53–84] 70 [58–84]
D0 urinary creatinine (mmol/24 h) 4.7 [0.85–5.1] 56.5 [35–74] 96 [88.5–100] 93 [78–100] 71 [62.5–81]
D1 urinary urea (mmol/24 h) 293 [196–363] 70 [50–90] 88 [76–100] 83 [67–100] 79 [68–92]
D1 urinary creatinine (mmol/24 h) 5.15 [3.01–6.3] 75 [55–90] 88 [72–100] 84 [68–100] 82 [70–93]
D2 urinary urea (mmol/24 h) 318 [292–591] 71 [52–90] 85 [69–96] 80 [64–94] 79 [68–92]
D2 urinary creatinine (mmol/24 h) 5.56 [4.67–6.57] 86 [71–100] 81 [65–96] 78 [65–94] 88 [75–100]
  1. PPV positive predictive value, NPV negative predictive value, CI confidence interval