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Annals of Intensive Care

Table 2 Drugs associated with serotonin toxicity used in the ICU/MCU

From: Unsuspected serotonin toxicity in the ICU

Serotonergic drugs

n = 44

Fentanyl (n)

36

Tramadol (n)

2

Metoclopramide (n)

7

Ondansetron (n)

7

CYP 3A4 inhibitor concomitantly (n)

16

CYP 2D6 inhibitor concomitantly (n)

24

  1. ICU intensive care unit, MCU medium care unit, n number, CYP 3A4 inhibitor cytochrome P450 3A4 iso-enzyme inhibitor, CYP2D6 inhibitor cytochrome P450 2D6 iso-enzyme inhibitor
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