Variable | Deceased patients nĀ =Ā 91 | Surviving patients nĀ =Ā 1660 | P value |
---|---|---|---|
Age [years (meanĀ Ā±Ā SD)] | 54Ā Ā±Ā 17 | 45Ā Ā±Ā 15 | <0.0001 |
Male gender [n (%)] | 46 (51) | 766 (46) | 0.42 |
SAPS II score, points (meanĀ Ā±Ā SD) | 69Ā Ā±Ā 21 | 36Ā Ā±Ā 15 | <0.0001 |
Mental disorder [n (%)] | |||
Ā Schizophrenia | 3 (3) | 94 (6) | 0.48 |
Ā Non-schizophrenia psychiatric disorder | 16 (21) | 218 (13) | 0.04 |
Ā Depression disorder | 50 (55) | 1008 (60) | 0.27 |
Ā Bipolar disorder | 12 (13) | 160 (10) | 0.26 |
Ā Anxiety disorder | 7 (8) | 180 (11) | 0.48 |
Substance dependence (alcohol and/or drug addiction) | 14 (15) | 478 (29) | 0.003 |
Transfer from psychiatric hospital or ward [n (%)] | 14 (15) | 116 (7) | 0.003 |
Psychoactive medication before admission [n (%)] | |||
Ā None | 9 (10) | 189 (11) | 0.66 |
Ā Benzodiazepines | 58 (64) | 1138 (68) | 0.33 |
Ā Neuroleptics | 26 (28) | 471 (28) | 0.97 |
Ā Antipsychotics other than neuroleptics | 10 (11) | 165 (10) | 0.74 |
Ā Lithium | 3 (3) | 78 (5) | 0.53 |
Ā SSRIs | 18 (20) | 402 (24) | 0.33 |
Ā SNRIs | 1 (1) | 33 (2) | 0.55 |
Ā Tri- or tetracyclics antidepressants | 11 (12) | 215 (13) | 0.81 |
Ā MAOIs | 8 (9) | 140 (8) | 0.90 |
Reason for admission [n (%)] | |||
Ā Deliberate self-poisoning with psychoactive medications | |||
Ā Ā Alone | 15 (16) | 1067 (64) | <0.0001 |
Ā Ā And/or with non-psychoactive medications | 10 (11) | 129 (8) | 0.27 |
Ā Ā And/or with pesticides, household, or industrial products | 0 (0) | 28 (2) | 0.40 |
Ā Ā And/or with hanging, drowning, jumping from buildings, or corrosive chemicals ingestion | 13 (14) | 18 (1) | <0.0001 |
Ā Respiratory failure | 14 (15) | 151 (9) | 0.06 |
Ā Shock | 15 (16) | 50 (3) | <0.0001 |
Ā CNS or peripheral disorder | 6 (7) | 76 (6) | 0.31 |
Ā Metabolic disorder | 1 (1) | 52 (3) | 0.52 |
Ā Out-of-hospital cardiac arrest | 14 (15) | 4 (0.2) | <0.0001 |
Ā Acute kidney injury | 0 (0) | 13 (0.5) | 0.99 |
Ā Non-deliberate psychoactive medication overdose | 2 (2) | 42 (2.5) | 0.99 |
Ā Miscellaneous | 3 (3) | 30 (2) | 0.24 |
Chemical pneumonitis and/or aspiration pneumonia [n (%)] | 28 (31) | 451 (27) | 0.45 |
Organ support in the ICU [n (%)] | |||
Ā Invasive mechanical ventilation | 91 (100) | 1115 (67) | <0.0001 |
Ā Vasopressors | 84 (92) | 294 (18) | <0.0001 |
Ā Renal replacement therapy | 38 (42) | 138 (8) | <0.0001 |
Acquired infection at any site | 14 (15) | 50 (3) | <0.0001 |