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Table 1 Clinical characteristics of the patients: data are presented as mean (S.D.) or median (IQR) where appropriate

From: Superior accuracy of mid-regional proadrenomedullin for mortality prediction in sepsis with varying levels of illness severity

  Survivors
n = 225
Non-survivors
n = 101
Total
n = 326
p
Patients from Valladolid (n, %) 102 (45.3%) 35 (34.7%) 137 0.071
Patients from Dijon (n, %) 123 (54.7%) 66 (65.3%) 189  
Male (n, %) 133 (59.1%) 68 (67.3%) 201 (61.4%) 0.098
Age (years) (mean, SD) 63 (14) 69 (12) 65.4 (14) <0.001
SOFA (mean, SD) 8 (3.4) 11 (3.5) 9 (3.7) <0.001
Septic shock (n, %) 152 (67.5%) 87 (86.1%) 239 (73.3%) 0.020
Mechanical ventilation (n, %) 150 (66.7%) 89 (88.1%) 239 (73.3%) <0.001
RRT (n, %) 40 (17.7%) 45 (44.6%) 85 (26.2%) <0.001
ICU stay (days) (mean, SD) 12.9 (18) 7.7 (6.7) 11.2 (15.6) 0.012
Neoplasia (n, %) 47 (21%) 35 (34.7%) 82 (25.2%) 0.007
Diabetes (n, %) 58 (25.8%) 29 (28.7%) 87 (26.7%) 0.330
COPD (n, %) 33 (14.7%) 16 (15.8%) 49 (15%) 0.450
Cardiovascular disease (n, %) 56 (25%) 41 (40.6%) 97 (29.8%) 0.030
Chronic renal failure (n, %) 16 (7.1%) 16 (15.8%) 32 (9.8%) 0.014
Immunosuppression (n, %) 21 (9.3%) 25 (24.8%) 46 (14.1%) <0.001
Respiratory infection (n, %) 98 (43.6%) 58 (57.4%) 156 (48%) 0.014
Urologic infection (n, %) 75 (33.3%) 36 (35.6%) 111 (34%) 0.380
Abdominal infection (n, %) 25 (11.1%) 10 (9.9%) 35 (10.7%) 0.450
Other infection (n, %) 32 (14%) 11 (10.9%) 43 (13%) 0.40
Primary or secondary bacteremia (n, %) 69 (30.7%) 38 (37.6%) 107 (32.8%) 0.130
Gram − bacteria (n, %) 62 (27.6%) 28 (27.7%) 90 (27.6%) 0.975
Gram + bacteria (n, %) 47 (20.9%) 22 (21.8%) 69 (21.2%) 0.855
Fungi (n, %) 3 (1.3%) 5 (5%) 8 (2.5%) 0.050
Virus (n, %) 15 (6.7%) 5 (5%) 20 (6.1%) 0.550
MR-proADM (nmol/L) (median, IQR) 2.68 (3.56) 7.44 (6.84) 3.62 (5.6) <0.001
Lactate (mmol/L) (median, IQR) 2.00 (1.54) 3.60 (5.53) 2.12 (2.28) <0.001
CRP (mg/dl) (median, IQR) 147.8 (193.6) 163.0 (181.9) 155.0 (189) 0.200
PCT (ng/ml) (median, IQR) 2.9 (17.5) 5.8 (36.7) 3.54 (27.5) 0.001
  1. Values expressed in percentages (%) indicate the proportion of survivors and non-survivors at 28 days for specific variables