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Annals of Intensive Care

Table 1 Clinical characteristics of the patients: data are presented as mean (S.D.) or median (IQR) where appropriate

From: Superior accuracy of mid-regional proadrenomedullin for mortality prediction in sepsis with varying levels of illness severity

 

Survivors

n = 225

Non-survivors

n = 101

Total

n = 326

p

Patients from Valladolid (n, %)

102 (45.3%)

35 (34.7%)

137

0.071

Patients from Dijon (n, %)

123 (54.7%)

66 (65.3%)

189

 

Male (n, %)

133 (59.1%)

68 (67.3%)

201 (61.4%)

0.098

Age (years) (mean, SD)

63 (14)

69 (12)

65.4 (14)

<0.001

SOFA (mean, SD)

8 (3.4)

11 (3.5)

9 (3.7)

<0.001

Septic shock (n, %)

152 (67.5%)

87 (86.1%)

239 (73.3%)

0.020

Mechanical ventilation (n, %)

150 (66.7%)

89 (88.1%)

239 (73.3%)

<0.001

RRT (n, %)

40 (17.7%)

45 (44.6%)

85 (26.2%)

<0.001

ICU stay (days) (mean, SD)

12.9 (18)

7.7 (6.7)

11.2 (15.6)

0.012

Neoplasia (n, %)

47 (21%)

35 (34.7%)

82 (25.2%)

0.007

Diabetes (n, %)

58 (25.8%)

29 (28.7%)

87 (26.7%)

0.330

COPD (n, %)

33 (14.7%)

16 (15.8%)

49 (15%)

0.450

Cardiovascular disease (n, %)

56 (25%)

41 (40.6%)

97 (29.8%)

0.030

Chronic renal failure (n, %)

16 (7.1%)

16 (15.8%)

32 (9.8%)

0.014

Immunosuppression (n, %)

21 (9.3%)

25 (24.8%)

46 (14.1%)

<0.001

Respiratory infection (n, %)

98 (43.6%)

58 (57.4%)

156 (48%)

0.014

Urologic infection (n, %)

75 (33.3%)

36 (35.6%)

111 (34%)

0.380

Abdominal infection (n, %)

25 (11.1%)

10 (9.9%)

35 (10.7%)

0.450

Other infection (n, %)

32 (14%)

11 (10.9%)

43 (13%)

0.40

Primary or secondary bacteremia (n, %)

69 (30.7%)

38 (37.6%)

107 (32.8%)

0.130

Gram − bacteria (n, %)

62 (27.6%)

28 (27.7%)

90 (27.6%)

0.975

Gram + bacteria (n, %)

47 (20.9%)

22 (21.8%)

69 (21.2%)

0.855

Fungi (n, %)

3 (1.3%)

5 (5%)

8 (2.5%)

0.050

Virus (n, %)

15 (6.7%)

5 (5%)

20 (6.1%)

0.550

MR-proADM (nmol/L) (median, IQR)

2.68 (3.56)

7.44 (6.84)

3.62 (5.6)

<0.001

Lactate (mmol/L) (median, IQR)

2.00 (1.54)

3.60 (5.53)

2.12 (2.28)

<0.001

CRP (mg/dl) (median, IQR)

147.8 (193.6)

163.0 (181.9)

155.0 (189)

0.200

PCT (ng/ml) (median, IQR)

2.9 (17.5)

5.8 (36.7)

3.54 (27.5)

0.001

  1. Values expressed in percentages (%) indicate the proportion of survivors and non-survivors at 28 days for specific variables
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