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Table 4 Patient characteristics during surgery

From: Goal-directed fluid restriction during brain surgery: a prospective randomized controlled trial

Variable Beginning of surgery 1 h 2 h 3 h 4 h End of surgery
Number
 GDFR group 73 (100%) 73 (100%) 73 (100%) 36 (49%) 25 (34%) 73 (100%)
 Control group 72 (100%) 72 (100%) 72 (100%) 37 (51%) 24 (33%) 72 (100%)
 p value 1.00 1.00 1.00 0.80 0.92 1.00
MAP (mmHg)
 GDFR group 83 ± 14 75 ± 9 77 ± 10 77 ± 11 73 ± 9 82 ± 11
 Control group 80 ± 15 78 ± 11 80 ± 14 76 ± 11 82 ± 11 78 ± 11
 p value 0.17 0.09 0.16 0.93 0.12 0.07
PETCO2 (mmHg)
 GDFR group 29 ± 3 29 ± 4 29 ± 3 29 ± 3 29 ± 3 31 ± 4
 Control group 30 ± 3 29 ± 3 29 ± 3 30 ± 3 32 ± 4 28 ± 3
 p value 0.20 0.68 0.69 0.44 0.06 0.79
Sodium (mmol/l)
 GDFR group 137.8 ± 4.8 134.5 ± 5.7 135.9 ± 4.7 136.8 ± 5.5 136.2 ± 3.3 137.3 ± 4.5
 Control group 136.0 ± 5.5 134.3 ± 5.8 136.1 ± 5.2 137.4 ± 5.3 139.0 ± 6.7 137.5 ± 5.1
 p value 0.03 0.81 0.86 0.64 0.07 0.84
Diuresis (ml/kg/h)
 GDFR group 0 5.58 ± 1.74 5.19 ± 1.37 4.97 ± 1.85 4.41 ± 1.73 4.12 ± 1.39
 Control group 0 5.76 ± 1.50 5.52 ± 1.77 5.03 ± 1.63 5.01 ± 1.45 4.12 ± 1.39
 p value 1 0.52 0.18 0.92 0.26 0.80
  1. Values are presented as mean ± standard deviation
  2. MAP mean arterial pressure, P ET CO 2 peak end-tidal CO2