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Table 2 Multivariable linear regression for longitudinal LV strain among patients, among all patients, and stratified according to preload (E/e′) and according to presence of shock (receiving a vasopressor at the time of echocardiogram)

From: Associations among left ventricular systolic function, tachycardia, and cardiac preload in septic patients

All patients with interpretable TTEs (N = 298) Coefficient p value
Heart rate 0.05 0.003
NEE during echo (per 0.01 mcg/kg/min increase) 0.02 0.17
APACHE II 0.03 0.37
E/e 0.11 0.02
Low preload E/e′ < 8 (N = 53)
 Heart rate −0.03 0.80
 NEE during echo (per 0.01 mcg/kg/min increase) 0.02 0.90
 APACHE II 0.12 0.56
Intermediate preload 8 ≤ E/e′ ≤ 14 (N = 135)
 Heart rate −0.01 0.87
 NEE during echo (per 0.01 mcg/kg/min increase) 0.005 0.86
 APACHE II 0.09 0.33
High preload E/e′ > 14 (N = 110)
 Heart rate −0.22 0.002
 NEE during echo (per 0.01 mcg/kg/min increase) 0.02 0.87
 APACHE II −0.02 0.87
Non-shock (N = 174)
 Heart rate 0.04 0.10
 APACHE II 0.06 0.20
 E/e 0.12 0.02
Shock (N = 124)
 Heart rate 0.07 0.01
 NEE during echo (per 0.01 mcg/kg/min increase) 0.02 0.36
 APACHE II −0.003 0.96
 E/e 0.04 0.70
  1. APACHE II Acute Physiology and Chronic Health Evaluation, version 2, NEE norepinephrine-equivalent dose. TTE transthoracic echocardiogram