Fig. 1

Severity criteria to compare hyperlactatemic patients without versus with a hypoperfusion context. a Mean norepinephrine doses for both subgroups at baseline, 6 and 24 h. Black boxes describe hypoperfusion-context subgroup; white boxes represent non-hypoperfusion context subgroup. b Comparison of the use of rescue therapy and several outcome parameters between subgroups. HVHF high-volume hemofiltration, Mortality hospital mortality, MV mechanical ventilation, ICU intensive care unit, LOS length of stay