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Table 1 Clinical, demographic, severity scores, perfusion and hemodynamic variables at baseline according to hypoperfusion context

From: A hypoperfusion context may aid to interpret hyperlactatemia in sepsis-3 septic shock patients: a proof-of-concept study

  Hypoperfusion context (70) Non-hypoperfusion context (20) p value
Age (years) 66 ± 17 65 ± 13 0.9
Charlson index 1.9 ± 2.2 1.6 ± 0.3 0.7
APACHE II score 22 ± 7 20 ± 5 0.2
SOFA score 9.5 ± 3.8 8.4 ± 2.6 0.1
Heart rate (beats/s) 104 ± 23 115 ± 24 0.07
MAP (mmHg) 75 ± 19 77 ± 21 0.6
SAP (mmHg) 108 ± 27 111 ± 27 0.6
DAP (mmHg) 59 ± 14 57 ± 12 0.6
Arterial lactate (mmol/L) 4.8 ± 2.8 4.7 ± 3.7 0.9
ScvO2 (%) 71.3 ± 9.5 74.8 ± 7 <0.05
P(cv-a) CO2 7.6 ± 2.5 5.5 ± 2.2 <0.001
CRT (s) 5.4 ± 2.3 4.2 ± 2.6 <0.001
NE (mcg/kg/min) 0.19 ± 0.24 0.09 ± 0.11 <0.05
  1. A p < 0.05 was considered as significant
  2. Values are expressed as mean ± SD
  3. APACHE Acute Physiology and Chronic Health Evaluation, SOFA Sequential Organ Failure Assessment, MAP mean arterial pressure, SAP systolic arterial pressure, DAP diastolic arterial pressure, P(cv-a)CO 2 central venous-arterial pCO2 gradient, CRT capillary refill time, NE norepinephrine