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Annals of Intensive Care

Table 1 Clinical, demographic, severity scores, perfusion and hemodynamic variables at baseline according to hypoperfusion context

From: A hypoperfusion context may aid to interpret hyperlactatemia in sepsis-3 septic shock patients: a proof-of-concept study

 

Hypoperfusion context (70)

Non-hypoperfusion context (20)

p value

Age (years)

66 ± 17

65 ± 13

0.9

Charlson index

1.9 ± 2.2

1.6 ± 0.3

0.7

APACHE II score

22 ± 7

20 ± 5

0.2

SOFA score

9.5 ± 3.8

8.4 ± 2.6

0.1

Heart rate (beats/s)

104 ± 23

115 ± 24

0.07

MAP (mmHg)

75 ± 19

77 ± 21

0.6

SAP (mmHg)

108 ± 27

111 ± 27

0.6

DAP (mmHg)

59 ± 14

57 ± 12

0.6

Arterial lactate (mmol/L)

4.8 ± 2.8

4.7 ± 3.7

0.9

ScvO2 (%)

71.3 ± 9.5

74.8 ± 7

<0.05

P(cv-a) CO2

7.6 ± 2.5

5.5 ± 2.2

<0.001

CRT (s)

5.4 ± 2.3

4.2 ± 2.6

<0.001

NE (mcg/kg/min)

0.19 ± 0.24

0.09 ± 0.11

<0.05

  1. A p < 0.05 was considered as significant
  2. Values are expressed as mean ± SD
  3. APACHE Acute Physiology and Chronic Health Evaluation, SOFA Sequential Organ Failure Assessment, MAP mean arterial pressure, SAP systolic arterial pressure, DAP diastolic arterial pressure, P(cv-a)CO 2 central venous-arterial pCO2 gradient, CRT capillary refill time, NE norepinephrine
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