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Table 2 Univariate analysis of muscle thickness, echo intensity and echo intensity standard deviation (SD) and z-scores, and area under the receiver operating characteristic curve (ROC–AUC)

From: Diagnostic accuracy of quantitative neuromuscular ultrasound for the diagnosis of intensive care unit-acquired weakness: a cross-sectional observational study

 

No ICU-AW

ICU-AW

P value

ROC–AUC (95% CI)

Thickness

    

 BB thickness [mean cm (SD)]

2.6 (0.6)

2.2 (0.5)

0.002*

68.0 (55.4–80.7)

 FCR thickness [mean cm (SD)]

1.1 (0.2)

1.0 (0.2)

0.035*

64.5 (50.4–78.7)

 RF thickness [mean cm (SD)]

3.1 (0.9)

2.8 (0.8)

0.258

55.6 (41.8–69.4)

 TA thickness [mean cm (SD)]

2.2 (0.4)

2.1 (0.4)

0.558

54.3 (40.3–68.3)

Z-score thickness

    

 BB z-score thickness [mean (SD)]

0.1 (0.6)

−0.3 (0.5)

0.011*

66.7 (53.7–79.6)

 FCR z-score thickness [mean (SD)]

−0.7 (1.2)

−1.3 (0.9)

0.033*

65.5 (51.3–79.7)

 RF z-score thickness [mean (SD)]

−0.5 (0.7)

−0.6 (0.8)

0.656

53.2 (39.4–67.1)

 TA z-score thickness [mean (SD)]

−0.4 (0.7)

−0.4 (1.0)

0.818

51.3 (37.5–65.1)

Echo intensity

    

 BB absolute echo intensity [mean gray scale level (SD)]

76.2 (14.1)

79.1 (16.4)

0.434

57.6 (44.0–71.3)

 FCR absolute echo intensity [mean gray scale level (SD)]

62.3 (12.6)

67.7 (13.6)

0.095

63.2 (49.6–76.9)

 RF absolute echo intensity [mean gray scale level (SD)]

77.2 (17.0)

83.9 (14.8)

0.094

60.2 (46.4–74.0)

 TA absolute echo intensity [mean gray scale level (SD)]

88.6 (12.4)

94.6 (12.1)

0.046*

60.8 (47.4–74.1)

Z-score echo intensity

    

 BB z-score echo intensity [mean (SD)]

0.5 (1.4)

0.7 (1.9)

0.519

56.3 (42.8–69.9)

 FCR z-score echo intensity [mean (SD)]

1.4 (1.6)

1.9 (2.0)

0.207

59.2 (45.2–73.2)

 RF z-score echo intensity [mean (SD)]

1.0 (1.6)

1.6 (1.8)

0.137

58.7 (45.0–72.4)

 TA z-score echo intensity [mean (SD)]

1.0 (1.2)

1.5 (1.4)

0.118

59.4 (45.9–72.9)

Echo intensity SD

    

 BB echo intensity SD [mean gray scale level(SD)]

29.0 (4.0)

28.5 (4.4)

0.585

53.3 (39.6–67.0)

 FCR echo intensity SD [mean gray scale level(SD)]

21.3 (3.1)

20.8 (3.9)

0.573

56.2 (42.2–70.2)

 RF echo intensity SD [mean gray scale level(SD)]

24.2 (3.3)

23.5 (3.5)

0.398

55.9 (42.0–69.8)

 TA echo intensity SD [mean gray scale level (SD)]

25.8 (3.6)

26.2 (3.9)

0.698

54.4 (40.5–68.3)

Z-score echo intensity SD

    

 BB z-score echo intensity SD [mean (SD)]

0.3 (1.5)

0.1 (1.5)

0.746

53.3 (39.6–67.0)

 FCR z-score echo intensity SD [mean (SD)]

0.8 (1.4)

0.6 (1.7)

0.716

55.0 (41.0–69.1)

 RF z-score echo intensity SD [mean (SD)]

0.1 (1.6)

0.04 (1.4)

0.890

54.2 (36.9–65.5)

 TA z-score echo intensity SD [mean (SD)]

−0.3 (1.1)

−0.2 (1.4)

0.777

55.0 (41.1–68.9)

  1. BB biceps brachii, FCR flexor carpi radialis, RF rectus femoris, TA tibialis anterior
  2. P < 0.05