The protective association of endogenous immunoglobulins against sepsis mortality is restricted to patients with moderate organ failure

Annals of Intensive Care

Table 4 Proportion of survivors and non-survivors at the hospital in the group of patients with SOFA score <8 depending on the immunoglobulin thresholds

	Thresholds	SOFA < 8: Hospital mortality
		Patients with prior immunosuppression included (n = 122)			Patients with prior immunosuppression excluded (n = 99)
		Non-survivors/Total “n” in each category	%	p	Non-survivors/Total “n” in each category	%	p
IgG (total)	<407 mg/dl	10/31	32.3	0.119	7/24	29.2	0.209
IgG (total)	≥407 mg/dl	18/91	19.8	0.119	13/75	17.3	0.209
IgG1	<332 mg/dl	10/30	33.3	0.119	7/24	29.2	0.209
IgG1	≥332 mg/dl	18/92	19.6	0.119	13/75	17.3	0.209
IgG2	<10 mg/dl	11/39	28.2	0.344	9/32	28.1	0.175
IgG2	≥10 mg/dl	17/83	20.5	0.344	11/67	16.4	0.175
IgM	<43 mg/dl	19/72	26.4	0.279	12/54	22.2	0.583
IgM	≥43 mg/dl	9/50	18.0	0.279	8/45	17.8	0.583
IgA	<219 mg/dl	14/49	28.6	0.226	10/39	25.6	0.277
IgA	≥219 mg/dl	14/73	19.2	0.226	10/60	16.7	0.277
ISC IgGAM	=0	9/17	52.9	0.002	6/12	50.0	0.006
ISC IgGAM	=1	19/105	18.1	0.002	14/87	16.1	0.006