Skip to main content

Table 2 Serum levels of individual bile acids in critically ill and control patients

From: Circulating bile acids predict outcome in critically ill patients

Parameter Cardiogenic shock Septic shock Post-surgery Controls
TCc, d, e, f 0.15 (0.09–0.49) 0.25 (0.11–0.73) 0.12 (0.08–0.32) 0.02 (0.02–0.02)
TCDCc, d, e, f 0.27 (0.1–0.79) 0.5 (0.08–1.83) 0.11 (0.05–0.54) 0.01 (0.01–0.01)
TDCd, e, f 0.19 (0.03–0.49) 0.13 (0.01–0.52) 0.12 (0.03–0.52) 0.03 (0.03–0.03)
TLCb, d, e, f 0.07 (0.05–0.11) 0.06 (0.03–0.08) 0.05 (0.03–0.07) 0.01 (0.01–0.01)
TUDCd, e 0.09 (0.07–0.12) 0.11 (0.07–0.17) 0.08 (0.07–0.3) 0.01 (0.01–0.01)
GCa, b, c, d, e, f 0.35 (0.24–0.71) 0.61 (0.32–2.3) 0.26 (019–0.37) 0.03 (0.03–0.1)
GCDCa, b, c, d, e, f 0.34 (0.12–1.29) 0.96 (0.21–2.5) 0.11 (0.05–0.7) 0.05 (0.05–0.36)
GDCd, e, f 0.29 (0.07–0.58) 0.56 (0.11–1.03) 0.22 (0.06–0.97) 0.01 (0.01–0.01)
GLC 0.09 (0.06–0.19) 0.09 (0.07–0.13) 0.13 (0.11–0.15)  
GUDCd, e, f 0.06 (0.04–0.11) 0.09 (0.04–0.13) 0.05 (0.04–0.1) 0.02 (0.02–0.02)
UDCd, e, f 0.04 (0.03–0.07) 0.07 (0.02–0.13) 0.03 (0.02–0.14) 0.01 (0.01–0.07)
CLb, c 0.04 (0.03–0.05) 0.04 (0.03–0.17) 0.03 (0.02–0.04) 0.04 (0.01–0.05)
CDC 0.09 (0.05–0.29) 0.22 (0.05–0.9) 0.1 (0.06–0.21) 0.1 (0.09–0.15)
DCd, e, f 0.1 (0.08–0.18) 0.09 (0.07–0.25) 0.09 (0.07–0.17) 0.05 (0.05–0.08)
LCb, d 0.05 (0.04–0.06) 0.04 (0.03–0.06) 0.04 (0.03–0.05) 0.04 (0.04–0.04)
TBAa, b, c, d, e 1.18 (0.63–4.08) 4.28 (1.15–6.96) 0.68 (0.38–1.51) 0.62 (0.41–0.92)
  1. Bile acids on admission are shown as median and IQR; bile acids (μmol/l)
  2. TC taurocholic acid, TCDC taurochenodeoxycholic acid, TDC taurodeoxycholic acid, TLC taurolithocholic acid, TUDC tauroursodeoxycholic acid, GCDC glycochenodeoxycholic acid, GC glycocholic acid, GDC glycodeoxycholic acid, GLC glycolithocholic acid, GUDC glycoursodeoxycholic acid, UDC ursodeoxycholic acid, CL cholic acid, CDC chenodeoxycholic acid, DC deoxycholic acid, LC lithocholic acid, TBA total bile acids
  3. a p < 0.05 cardiogenic shock versus septic shock
  4. b p < 0.05 cardiogenic shock versus post-surgery
  5. c p < 0.05 septic shock versus post-surgery
  6. d p < 0.05 cardiogenic shock versus controls
  7. e p < 0.05 septic shock versus controls
  8. f p < 0.05 post-surgery versus controls