From: Functional outcome of patients with prolonged hypoglycemic encephalopathy
No care limitation (n = 27) | Withholding/withdrawing care (n = 22) | P value | |
---|---|---|---|
Male | 13 (48) | 14 (64) | 0.38 |
Age (years) | 53 [42–64] | 58 [49–72] | 0.15 |
Chronic alcohol abuse | 20 (74) | 9 (41) | 0.04 |
Diabetes | 14 (52) | 15 (68) | 0.38 |
SAPS II | 53 [47–60] | 57 [51–63] | 0.17 |
mRS prior to ICU admission | 1 [0–1] | 1 [0–2] | 0.40 |
Duration of hypoglycemia, min (n = 27) | 90 [31–525] | 720 [480–810] | 0.07 |
Initial glycemia (g/L) | 0.20 ± 0.13 | 0.22 ± 0.12 | 0.45 |
Glycemia on ICU admission (g/L) | 1.42 ± 1.49 | 1.24 ± 1.18 | 0.86 |
GCS | |||
Initial | 4 ± 1 | 4 ± 1 | 0.06 |
After glycemia normalization | 5 ± 2 | 5 ± 1 | 0.55 |
Seizures | 7 (26) | 1 (4) | 0.04 |
Temperature (°C) | |||
Initial | 36.5 ± 1.2 | 36.9 ± 1.5 | 0.49 |
Highest during first 24 h | 37.8 ± 1.2 | 38.1 ± 1.4 | 0.28 |
Initial arterial pH | 7.36 ± 0.14 | 7.41 ± 0.09 | 0.39 |
Initial lactate level (mmol/L) | 3.05 ± 3.04 | 1.81 ± 1.09 | 0.18 |
Time to final glycemia normalization (min) | 390 [112–720] | 180 [67–480] | 0.42 |
Mechanical ventilation | 24 (89) | 22 (100) | 0.24 |
Length of mechanical ventilation (days) | 5.5 [2–8] | 11 [7–16] | 0.002 |
Normal EEG (n = 34) | 1 (3.7) | 0 (0) | 0.41 |
Normal brain imaging (n = 45) | 17 (63) | 8 (36) | 0.04 |
Acquired ICU complications | |||
Pneumonia | 12 (44) | 13 (59) | 0.39 |
Septic shock | 5 (19) | 3 (14) | 0.72 |
ICU length of stay (days) | 7 [4–13] | 14 [9–24] | 0.007 |