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Table 2 Plasma, arterial blood gas and urine data at 200 min postresuscitation

From: Assessment of renal hemodynamic toxicity of fluid challenge with 0.9% NaCl compared to balanced crystalloid (PlasmaLyte®) in a rat model with severe sepsis

  0.9% NaCl
n = 20
PlasmaLyte®
n = 20
p
Total fluid requirements (mL) during resuscitation 23 ± 11 23 ± 10 0.99
Plasma at T2
 Sodium (mmol/L) 141 ± 2 138 ± 3 0.017
 Chloride (mmol/L) 117 ± 3 104 ± 3 <0.001
 Potassium (mmol/L) 6.0 ± 0.6 5.3 ± 0.6 0.004
 BUN (mmol/L) 12 ± 3 12 ± 4 0.77
 Creatinine (µmol/L) 34 ± 7 36 ± 6 0.27
 Phosphate (mmol/L) 3.5 ± 0.5 3.6 ± 0.5 0.36
 Calcium (mmol/L) 1.9 ± 0.1 1.9 ± 0.2 0.64
 Osmolarity (mmol/L) 306 ± 8 299 ± 8 0.027
 Hematocrit (%) 44 ± 6 48 ± 4 0.16
 Plasma protein (g/L) 27 ± 3 29 ± 3 0.33
Arterial blood gas
 pH 7.34 ± 0.05 7.44 ± 0.04 <0.001
 Bicarbonate (mmol/L) 20 ± 2 26 ± 2 <0.001
 PaCO2 (mm Hg) 38 ± 5 39 ± 5 0.62
Urine at T2
 Urine output during resuscitation (mL) 1.7 ± 0.4 2.5 ± 0.6 0.002
 Sodium (mmol/L) 52 ± 28 41 ± 15 0.4
 Chloride (mmol/L) 182 ± 56 26 ± 6 <0.001
 Potassium (mmol/L) 168 ± 48 175 ± 54 0.75
 BUN (mmol/L) 533 ± 196 383 ± 161 0.066
 Creatinine (mmol/L) 6.0 ± 2.0 4.2 ± 1.3 0.019
 Sodium/potassium ratio 0.38 ± 0.24 0.29 ± 0.17 0.44
Measured clearance at T2
 Inulin (mL/min) 5.2 ± 2.9 4.4 ± 1.9 0.49
 Creatinine (mL/min) 2.3 ± 1.1 2.3 ± 0.8 0.95