Fig. 2

Chronological scale of the two cases of ESBL cross-transmission in the ICU. The figure represents the timescale of ESBL cross-transmission. Patients are identified with their inclusion number. The two cases of cross-transmission (P203 and P220) are colored in dark blue, whereas the corresponding index patient (P219) is materialized in light blue. Index patient is defined as already known carriers of ESBL who shared at least one day of hospitalization with the case of ESBL acquisition. Each line represents the stay of one patient. A day of hospitalization is represented by a square. Each block separated by bold lines represents a case of cross-transmission. The ICU stays of the cross-transmitted ESBL patients are green, whereas the stay of the index patient is colored in pink if the index patient is hospitalized in a different unit, in orange for hospitalization in the same unit but not in the same room. The dotted red line indicates the arrival in the ICU of patients acquiring ESBL. A arrival, Ec Escherichia coli, Ecl Enterobacter cloacae, Cf Citrobacter freundii, CTXm cefotaximase München, ESBL-PE extended-spectrum beta-lactamase-producing Enterobacteriaceae, ICU intensive care unit, Kp Klebsiella pneumoniae, P patient, Pm Proteus mirabilis