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Table 3 Transfusions and blood products and of ARDS patients on ECMO/pECLA with either argatroban or heparin

From: Efficacy and safety of argatroban in patients with acute respiratory distress syndrome and extracorporeal lung support

 

Argatroban (n = 39)

Heparin (n = 39)

p values

n per patient-day on extracorporeal lung support

n per patient-day on extracorporeal lung support

Transfusions

 Packed red blood cells

0.98

1.2

0.61

 Fresh-frozen plasma

1.8

1.77

0.86

 Platelet concentrate

0.28

0.49

0.21

Blood products and coagulation factors

 Fibrinogen (g)

0.05

0.01

0.60

 Prothrombin complex concentrate (IU)

1.96

3.53

0.75

 Antithrombin III (IU)

9.7

117

<0.01*

  1. Discrete variables are presented as absolute numbers per patient-day on extracorporeal lung support and were analyzed with Fisher’s exact test for nonparametric samples
  2. p < 0.05; g: gram; IU international units; complete data were available for all 78 patients