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Table 4 Multivariate analysis evaluating the factors associated with increase(s) in cisatracurium dosage

From: How to reduce cisatracurium consumption in ARDS patients: the TOF-ARDS study

Variables Odds ratio 95% CI p value
First model with PEEP at day 1
 Weight, per 1 kg increase 1.14 0.98–1.31 0.07
 Bicarbonates, per 1 mmol/L 1.06 0.87–1.29 0.56
 PEEP day 1, per 1 cm H2O increase 0.42 0.18–0.98 0.044
 Severe ARDS 0.22 0.017–2.89 0.25
 Use of prone position 1.73 0.14–22.06 0.67
 Other organ failure, per organ 6.02 0.68–53.1 0.10
Second model with driving pressure at day 1
 Weight, per 1 kg increase 1.07 0.99–1.16 0.065
 Bicarbonates, per 1 mmol/L 1.06 0.87–1.29 0.58
 Driving pressure day 1, per 1 cm H2O increase 1.99 1.01–3.9 0.045
 Severe ARDS 0.32 0.017–6.02 0.44
 Use of prone position 6.98 0.32–153.4 0.22
 Other organ failure, per organ 1.96 0.35–10.85 0.44
  1. ARDS Acute Respiratory Distress Syndrome, PEEP positive end-expiratory pressure