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Table 6 Summary diagnostic accuracy of the included studies for biomarkers, presepsin, procalcitonin, and C-reactive protein

From: Comparison of diagnostic accuracy in sepsis between presepsin, procalcitonin, and C-reactive protein: a systematic review and meta-analysis

References Sepsis/control (n) Presepsin Procalcitonin C-reactive protein
Sensitivity Specificity AUC Sensitivity Specificity AUC Sensitivity Specificity AUC
Shozushima et al. [17] 101/41 0.80 0.81 0.88 0.65 0.82
Endo et al. [29] 115/70 0.88 0.81 0.91 0.86 0.79 0.91
Liu et al. [33] 680/279 0.71 0.86 0.82 0.60 0.78 0.72
Ulla et al. [38] 106/83 0.79 0.62 0.70 0.89 0.76 0.88
Vodnik et al. [39] 30/100 1 0.98 0.99 0.87 0.97 0.96 0.96
Behnes et al. [25] 81/15 0.90 0.60 0.84 0.86
Brenner et al. [26] 60/60 0.91 0.67 0.83 0.77 0.78 0.84 0.67 0.85 0.79
Romualdo et al. [35] 37/189 0.81 0.63 0.75 0.76 0.64 0.79 0.62 0.52 0.60
Ishikura et al. [31] 43/39 0.93 0.76 0.89
Kweon et al. [32] 73/45 0.88 0.82 0.94 0.86 0.87 0.92 0.99 0.67 0.85
Cakir Madenci et al. [27] 26/11 0.77 0.76 0.83 0.76 0.79 0.85 0.92 0.58 0.82
Nakamura et al. [34] 37/75 0.70 0.81 0.78
Sargentini et al. [36] 60/44 0.86 0.72 0.89 0.80 0.80 0.91
Godnic et al. [30] 40/7 0.85 0.63 0.71 0.58 0.67 0.63 0.77 0.75 0.73
Takahashi et al. [37] 359/97 0.80 0.83 0.89 0.77 0.76 0.85 0.72 0.95 0.82
Carpio et al. [28] 114/9 0.81 0.75 0.83
Kada Klouche et al. [41] 100/44 0.90 0.55 0.75 0.80 0.59 0.80
Romualdo et al. [40] 70/130 0.67 0.81 0.78 0.67 0.84 0.82 0.26 0.92 0.59
  1. AUC, area under the receiver operating characteristic curve; –, not report