Skip to main content

Table 4 Diagnostic and overall accuracy of [TIMP-2]·[IGFBP7] for AKI compared with gold standard AKIN classification

From: Cell-cycle arrest biomarkers in urine to predict acute kidney injury in septic and non-septic critically ill patients

[TIMP-2]·[IGFBP7] cut-off value ((ng/mL)2/1000) Se % 95% CI Sp % 95% CI AUC 95% CI
0.3—to predict AKI 81.6 78.2–85.0 59.2 54.9–63.5 0.80 0.71–0.89
0.4—to predict AKI 73.5 69.7–77.5 71.4 67.4–75.4   
0.8—to predict AKIN ≥ 2 72.0 68.1–75.9 78.1 74.6–81.8 0.81 0.70–0.91
2.0—to predict AKIN ≥ 2 48.0 43.6–52.4 90.4 87.8–93.0   
  1. AUC area under curve of ROC analysis; CI confidence interval; Se sensitivity; Sp specificity