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Table 1 Baseline characteristics of cohorts

From: Prognostic impact of isolated right ventricular dysfunction in sepsis and septic shock: an 8-year historical cohort study

Parameter Isolated RV dysfunction (n = 100) RV/LV dysfunction (n = 114) No RV dysfunction (n = 174) p
Age (years) 65.6 (55.2–77.5) 69.3 (55.3–77.4) 64.7 (53.4–74.7) 0.22
Male sex 48 (48) 59 (51.8) 91 (52.3) 0.78
Admitting location     0.13
Emergency room 53 (53) 52 (45.6) 86 (49.4)
Hospital floors 21 (21) 28 (24.6) 55 (31.6)  
Outside transfer 26 (26) 34 (29.8) 33 (19)
Source of sepsis     0.22
 Respiratory 27 (27) 27 (23.7) 27 (15.5)
 Abdominal 2 (2) 3 (2.6) 8 (4.6)
 Genitourinary 4 (4) 6 (5.3) 18 (10.3)
 Skin/soft tissue 3 (3) 2 (1.8) 9 (5.2)
 Other/unknown 38 (38) 45 (39.5) 69 (39.7)
 Not available 26 (26) 31 (27.2) 43 (24.7)
Body mass index (kg/m2) 30.8 (24.6–36.7) 28.6 (25–33.5) 28.7 (24–33.7) 0.29
Body surface area (m2) 2.0 (1.8–2.3) 1.9 (1.8–2.2) 1.9 (1.8–2.2) 0.27
Hypertension 35 (35) 51 (44.7) 71 (40.8) 0.35
Coronary artery disease 10 (10) 23 (20.2) 23 (13.2) 0.09
Prior myocardial infarction 7 (7) 13 (11.4) 14 (8.1) 0.48
Obstructive sleep apnea 10 (10) 19 (16.7) 22 (12.6) 0.34
Chronic lung disease 24 (24) 27 (23.7) 41 (23.6) 0.99
Charlson comorbidity index 5 (3–7) 6 (4–8) 5 (3–8) 0.40
APACHE-III score 85.5 (68.3–110) 84 (69–104) 81 (66–105) 0.54
SOFA score (day 1) 9 (7–12) 9 (7–11) 8 (5–12) 0.07
Septic shock 80 (80) 82 (71.9) 119 (68.4) 0.11
ARDS 30 (30) 36 (31.6) 49 (28.2) 0.82
 Mild (n) 6 10 15
 Moderate (n) 18 18 22
 Severe (n) 6 8 12
Acute kidney injury 62 (62) 74 (64.9) 110 (63.2) 0.91
Admission troponin-T (ng/mL) 0.06 (0.02–0.17) 0.05 (0.03–0.15) 0.06 (0.02–0.16) 0.90
Highest lactate (mmol/L) 2.8 (1.8–5.8) 3.2 (1.8–5.5) 3 (1.6–5.4) 0.86
pH 7.34 (7.26–7.39) 7.33 (7.26–7.4) 7.36 (7.29–7.42) 0.03
pCO2 (mmHg) 39 (33–45) 36 (30–44) 36 (31–42) 0.04
PaO2/FiO2 ratio (mmHg) 170 (127–287) 196 (129–283) 197 (111–288) 0.87
Mechanical ventilation 67 (67) 58 (50.9) 88 (50.6) 0.03
PEEP (cm H2O) 7.5 (5–10) 8 (5–10) 7.5 (5–10) 0.34
PIP (cm H2O) 25 (18–31) 23 (17–29) 21 (14–27) 0.04
Plateau pressure (cm H2O) 23 (17–30) 20 (16–26) 21 (15–25) 0.17
Mean airway pressure (cm H2O) 14 (10–19) 14 (11–17) 13 (10–17) 0.39
Total norepinephrine (mg) 18.5 (4.7–46.8) 11.6 (3.8–33.5) 14.3 (3.8–44.3) 0.45
Crystalloid 24 h (L) 4.2 (2.4–6.8) 4.2 (2–6.2) 4.2 (2.1–7.2) 0.71
  1. Represented as: total (percentage) or median (interquartile range)
  2. APACHE-III Acute Physiology and Chronic Health Evaluation III therapy, ARDS acute respiratory distress syndrome, FiO 2 fraction of inspired oxygen, LV left ventricular, paO 2 partial pressure of arterial oxygen, pCO 2 partial pressure of carbon dioxide, PEEP positive end-expiratory pressure, PIP peak inspiratory pressure, RV right ventricular, SOFA Sequential Organ Failure Assessment