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Table 2 Echocardiographic parameters of cohorts*

From: Prognostic impact of isolated right ventricular dysfunction in sepsis and septic shock: an 8-year historical cohort study

Parameter Isolated RV dysfunction (n = 100) RV/LV dysfunction (n = 114) No RV dysfunction (n = 174) p
N Value N Value N Value
RV enlargement 100 82 (82) 113 79 (69.9) 158 0 (0) <0.001
RV dysfunction 100 58 (58) 114 80 (70.2) 157 0 (0) <0.001
TR velocity (m/s) 36 2.8 (2.4–3.1) 66 2.7 (2.3–2.9) 33 2.7 (2.4–2.9) 0.22
RV systolic pressure (mmHg) 82 45 (33–58) 107 41 (33–48) 113 39 (32–46) 0.01
Estimated RA pressure (mmHg) 84 10 (5–15) 108 10 (5–14) 122 10 (5–10) 0.006
TAPSE (mm) 10 20 (13.3–23.3) 25 18 (15–19.5) 6 25.5 (21.5–28.5) 0.007
TV systolic velocity TDI (m/s) 35 0.14 (0.12–0.15) 60 0.13 (0.10–0.14) 27 0.17 (0.16–0.18) <0.001
LV ejection fraction (%) 81 61 (56–67) 81 53 (45–61) 113 60 (55–65) <0.001
LV end-systolic diameter (mm) 81 28 (24.5–32.5) 100 32 (28–37) 126 47 (43–51) <0.001
LV end-diastolic diameter (mm) 87 46 (41–50) 109 47 (43–51) 111 30 (26–33) 0.17
LV mass index (g/m2) 73 83 (67–101.5) 100 88 (70–100) 108 90 (74–102) 0.26
LV stroke volume index (mL/m2) 73 42 (34.5–50) 104 37.5 (30.3–46) 116 41 (36–48) 0.009
Cardiac index (L/min/m2) 73 3.7 (3.1–4.5) 104 3.3 (2.8–4.1) 116 3.8 (3.2–4.4) <0.001
Left atrial volume index (mL/m2) 39 21 (23–37) 63 35 (28–43) 61 33 (29–38.5) 0.16
LV peak systolic velocity (m/s) 66 0.13 (0.11–0.15) 85 0.12 (0.1–0.14) 70 0.15 (0.13–0.17) <0.001
Mitral E velocity (m/s) 70 0.8 (0.6–1.0) 88 0.8 (0.7–1.0) 108 0.9 (0.8–1.1) 0.001
Mitral A velocity (m/s) 63 0.8 (0.6–0.9) 69 0.8 (0.6–0.9) 99 0.8 (0.7–1.0) 0.04
Mitral E/A ratio 63 1.0 (0.8–1.3) 69 1.0 (0.8–1.5) 99 1.0 (0.8–1.4) 0.44
Mitral e′ velocity (medial) (m/s) 68 0.08 (0.06–0.09) 91 0.07 (0.05–0.08) 105 0.07 (0.06–0.1) 0.02
Mitral e′ velocity (lateral) (m/s) 52 0.10 (0.08–0.13) 67 0.09 (0.08–0.10) 76 0.1 (0.08–0.12) 0.01
Mitral E/e′ ratio (medial) 65 10 (8.3–13.8) 84 12.5 (10–15) 100 12.1 (9.2–15) 0.04
Mitral E/e′ ratio (lateral) 49 7.9 (5.7–10) 61 9 (7.6–11.6) 72 9.2 (7.2–12) 0.01
  1. Represented as: total (percentage) or median (interquartile range)
  2. LV left ventricle, RA, right atrial, RV right ventricular, TAPSE tricuspid annular plane systolic excursion, TDI tissue Doppler imaging, TR tricuspid regurgitation, TV tricuspid valve
  3. *Not all parameters were measured in all patients. Individual n for each cohort is presented in the table