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Table 2 Characteristics of patients with cirrhosis stratified according to good 28-day outcome and bad 28-day outcome

From: Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis

Parameters

Overall (n = 47)

Good 28-day outcome (n = 9)

Bad 28-day outcome (n = 38)

p value*

Aetiology of cirrhosis, n %

   

0.33

 Alcoholic

35 (74)

7 (78)

28 (74)

 

 Viral

6 (13)

2 (22)

4 (10)

 

 Other (cryptogenic, cardiac, etc.)

6 (13)

0 (0)

6 (16)

 

Hepatocellular carcinoma, n %

3 (6)

0 (0)

3 (8)

0.38

Liver TX during follow-up, n %

0 (0)

0 (0)

0 (0)

 

TIPS, n %

3 (6)

0 (0)

3 (8)

0.38

CLIF-SOFA—admission median; IQR

10 (6–12.5)

4 (3–4)

11 (9–13)

< 0.001

CLIF-SOFA—24 h median; IQR

10 (4.5–14)

4 (2–7)

12 (8.25–15.5)

0.01

CLIF-SOFA—48 h median; IQR

7 (2–12.5)

1 (1–7)

11 (6–13.75)

0.01

CTP—before admission, n %

   

0.05

 A

17 (36)

6 (67)

11 (29)

 

 B

17 (36)

3 (33)

14 (37)

 

 C

13 (28)

0 (0)

13 (34)

 

CTP points—before admission median; IQR

7 (5.5–10)

6 (5–7)

8 (6–11)

0.03

MELD—admission median; IQR

19 (10.5–24)

10 (9–10)

21 (14–24)

< 0.001

SOFA—admission median; IQR

11 (7.5–13)

4 (3–7)

12 (10–13.75)

< 0.001

SAPS II—admission median; IQR

87 (77.5–100)

66 (66–75)

92 (85–102.75)

< 0.001

Ascites—before admission, n %

   

0.33

 None

15 (32)

4 (44)

11 (29)

 

 Mild

25 (53)

5 (56)

20 (53)

 

 Severe

7 (15)

0 (0)

7 (18)

 

HE—before admission, n %

   

0.22

 None

25 (53)

7 (78)

18 (47)

 

 I–II

17 (36)

2 (22)

15 (40)

 

 III–IV

5 (11)

0 (0)

5 (13)

 

ACLF—on admission, n %

   

< 0.001

 Grade 1

11 (23)

1 (11)

10 (26)

 

 Grade 2

11 (23)

0 (0)

11 (30)

 

 Grade 3

11 (23)

0 (0)

11 (30)

 

 No ACLF

14 (30)

8 (89)

6 (16)

 

ACLF—during follow-up, n %

   

< 0.001

 Grade 1

1 (2)

1 (11)

0 (0)

 

 Grade 2

3 (6)

1 (11)

2 (5)

 

 Grade 3

0 (0)

0 (0)

0 (0)

 

 No ACLF

10 (21)

6 (67)

4 (11)

 

Ischaemic time, min median; IQR

 No flow

0 (0–3.5)

0 (0–0)

0 (0–5)

< 0.01

 Low flow

11 (3–23)

1 (1–3)

16 (8–23.5)

0.06

 Time to ROSC

15 (3–27)

1 (1–3)

19.5 (11–28)

< 0.05

Initial rhythm, n %

 VT/VF

10 (21)

3 (33)

7 (18)

0.569

 PEA/Asystole

35 (75)

4 (45)

31 (82)

< 0.05

 Other/unknown

2 (4)

2 (22)

0 (0)

0.305

Witnessed cardiac arrest, n %

42 (89)

9 (100)

33 (87)

0.118

Defibrillation, n %

14 (30)

3 (33)

11 (29)

0.569

Therapeutic hypothermia, n %

18 (38)

1 (11)

17 (45)

< 0.01

  1. CPC cerebral performance categories, TX transplantation, TIPS transjugular intrahepatic portosystemic shunt, CLIF-SOFA chronic liver failure-Sequential Organ Failure Assessment, CTP Child–Turcotte–Pugh, MELD model for end-stage liver disease, SOFA Sequential Organ Failure Assessment, SAPS Simplified Acute Physiology Score, HE hepatic encephalopathy, ACLF acute-on-chronic liver failure
  2. * CPC 1/2 versus CPC 3/4 or mortality