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Fig. 4 | Annals of Intensive Care

Fig. 4

From: Thrombomodulin favors leukocyte microvesicle fibrinolytic activity, reduces NETosis and prevents septic shock-induced coagulopathy in rats

Fig. 4

Plasma neutrophil extracellular traps and nucleosomes. NETs were measured in plasma using indirect markers: a neutrophil elastase (NE)/DNA complexes and b citrullinated histones H3 (H3c)/DNA complexes. c Nucleosomes were also measured on plasma samples. Results were reported to neutrophil ratio because of the significant neutropenia observed in septic groups. n = 10 per subset. Results are expressed in mean ± SD. *p < 0.05 versus sham–NaCl group and # p < 0.05 versus CLP–NaCl group

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