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Table 2 Patients with normal systolic function and their echocardiographic parameters on day 1

From: Application of updated guidelines on diastolic dysfunction in patients with severe sepsis and septic shock

Echo parameter Normal diastolic function n = 11
(25%)
Grade I diastolic dysfunction n = 7
(16%)
Grade 2 diastolic dysfunction n = 12
(27%)
Grade 3 diastolic dysfunction (n = 1)
(2%)
Indeterminate diastolic function (n = 13)
(30%)
Septal hypertrophy 0 7 (100%) 5 (42%) 0 4 (31%)
E/e′ > 14 0 0 8 (67%) 1 (100%) 3 (23%)
Mean E/e 9.5 ± 2.4 10 ± 2.3 15.6 ± 4.6 22.4 13 ± 4.9
Septal e′ < 7 cm/s (n) 6 (55%) 5 (71%) 10 (83%) 1 10 (77%)
Septal e′ (cm/s) 0.08 ± 0.02 0.06 ± 0.02 0.055 ± 0.01 0.03 0.055 ± 0.01
Lateral e′ < 10 cm/s (n) 5 (45%) 4 (57%) 11 (92%) 1 10 (77%)
Mean lateral e′ (cm/s) 0.09 ± 0.03 0.08 ± 0.03 0.08 ± 0.02 0.07 0.085 ± 0.02
Increased left atrial volume (n) 3 (27%) 3 (43%) 11 (92%) 1 8 (67%)
Mean left atrial volume (ml) 51 ± 12 52 ± 20 87.5 ± 29 111 56 ± 15
TR velocity > 2.8 (n) 1 (9%) 0 (0%) 9 (75%) 1 0
TR velocity average (m/s) 2.43 (1.97,2.67) 2.4 (1.6, 2.74) 2.96 (2.8, 3.22) 3.29 2.35 (2.2, 2.52)
Cardiac output (L/min) 5.5 ± 1.5 6.9 ± 2.6 6.2 ± 1.65 N/A 6.05 ± 1.2
  1. Diastolic dysfunction assessed by 2016 ASE/EACVI guidelines
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