Table 1 Percentages of PK/PD target attainment for various MIC and CrCL for cefazolin administered continuously (100 mg/kg/day)
From: Proceedings of Réanimation 2018, the French Intensive Care Society International Congress
CrCL < 150 ml/min N = 15 | 150 ≤ CrCL < 200 ml/min N = 22 | CrCL ≥ 200 ml/min N = 26 | |
|---|---|---|---|
Targeted MIC ≥ 0.5 µg/ml | 100 [100–100] | 100 [100–100] | 100 [100–100] |
Targeted MIC ≥ 1 µg/ml | 93 [81–100] | 86 [72–100] | 92 [82–100] |
Targeted MIC ≥ 2 µg/ml | 80 [60–100] | 41 [20–62] | 12 [0–24] |
Targeted MIC ≥ 4 µg/ml | 20 [0–40] | 5 [0–13] | 0 [0–0] |