Table 1 Characteristics and outcomes of patients according to their antimicrobial regimen
From: Proceedings of Réanimation 2018, the French Intensive Care Society International Congress
All patients | Carbapenem-only | Carbapenem-definite | CSA-only | CSA-definite | p | |
|---|---|---|---|---|---|---|
N = 66 | N = 22 | N = 17 | N = 9 | N = 18 | ||
Age, years | 57 [49–63] | 54.5 [45–62] | 61 [55–64] | 61 [51–74] | 55 [34–61] | NS |
Female sex | 46 (70) | 8 (36) | 3 (18) | 1 (11) | 8 (44) | NS |
SAPS II score | 58.5 [44–71] | 58.5 [41–69] | 58 [45.5–72.5] | 66 [43.5–79] | 54.5 [47–70] | NS |
SOFA score | 11.5 [7–15] | 9 [6–15] | 13 [7–16] | 13 [4.75–14.25] | 11.5 [7–16] | NS |
Septic shock | 38 (58) | 10 (56) | 4 (57) | 10 (59) | 14 (58) | NS |
Immunodepression | 21 (33) | 7 (39) | 1 (17) | 7 (41) | 6 (26) | NS |
Site of infection | 0.02 | |||||
Lung | 51 (77) | 17 (77) | 16 (94) | 7 (78) | 11(61) | |
Primary bacteremia | 12 (18) | 4 (18) | 1 (6) | 0 | 7 (39) | |
Other | 4 (6) | 1 (5) | 0 | 2 (22) | 0 | |
Treatment duration, days | 8 [6–10] | 7 [6–10] | 9 [7–10] | 7 [6–9] | 8 [7–11] | NS |
Treatment failure (mortality or relapse) | 34 (52) | 15 (68) | 9 (53) | 4 (44) | 6 (33) | NS |