Fig. 4

Blood transcriptomics of sepsis patients discordant for statin therapy in the propensity-matched cohort. a Volcano plot representation of differential gene expression in patients treated with statins (N = 95) and patients not treated with statins (N = 95), both relative to healthy subjects. b Dot plot illustrating the strong correlation between expression changes in sepsis patients discordant for statin therapy, relative to healthy subjects. Rho, Spearman’s rho. c Ingenuity pathway analysis of genes with elevated expression (red bars) and decreased expression (turquoise) (N = 190)