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Table 2 Outcomes of sepsis patients admitted to the ICU stratified according to prior use of statins

From: The host response in critically ill sepsis patients on statin therapy: a prospective observational study

Outcomes Unmatched cohort Propensity-matched cohort
Statins
N = 351
No statins
N = 709
p Statins
N = 194
No statins
N = 194
p
Length of stay ICU, median, days [IQR] 4 [2–9] 5 [2–10] .28 4 [2–11] 5 [2–11] .58
Organ failure during admission (%) 307 (87.5) 634 (89.4) .32 175 (90.2) 180 (92.8) 1
Shock during admission (%) 150 (42.7) 296 (41.7) .80 93 (47.9) 97 (50) .76
Acute lung injury during admission (%) 107 (30.5) 232 (32.7) .49 66 (34) 55 (28.4) .29
Acute kidney injury during admission (%) 183 (52.1) 327 (46.1) .07 99 (51) 106 (54.6) .53
Mortality
 ICU mortality (%) 65 (18.5) 149 (21) .36 35 (18) 48 (24.7) .13
 Hospital mortality (%) 106 (30.2) 226 (31.9) .58 62 (32) 73 (37.6) .31
 30-day mortality (%) 92 (26.2) 198 (27.9) .60 48 (24.7) 67 (34.5) .051
 60-day mortality (%) 112 (31.9) 235 (33.1) .71 61 (31.4) 74 (38.1) .24
 90-day mortality (%) 129 (36.8) 255 (36) .84 74 (38.1) 77 (39.7) .83
  1. ICU intensive care unit, IQR interquartile range