Table 2 Outcomes of sepsis patients admitted to the ICU stratified according to prior use of statins
Outcomes | Unmatched cohort | Propensity-matched cohort | ||||
|---|---|---|---|---|---|---|
Statins NÂ =Â 351 | No statins NÂ =Â 709 | p | Statins NÂ =Â 194 | No statins NÂ =Â 194 | p | |
Length of stay ICU, median, days [IQR] | 4 [2–9] | 5 [2–10] | .28 | 4 [2–11] | 5 [2–11] | .58 |
Organ failure during admission (%) | 307 (87.5) | 634 (89.4) | .32 | 175 (90.2) | 180 (92.8) | 1 |
Shock during admission (%) | 150 (42.7) | 296 (41.7) | .80 | 93 (47.9) | 97 (50) | .76 |
Acute lung injury during admission (%) | 107 (30.5) | 232 (32.7) | .49 | 66 (34) | 55 (28.4) | .29 |
Acute kidney injury during admission (%) | 183 (52.1) | 327 (46.1) | .07 | 99 (51) | 106 (54.6) | .53 |
Mortality | ||||||
 ICU mortality (%) | 65 (18.5) | 149 (21) | .36 | 35 (18) | 48 (24.7) | .13 |
 Hospital mortality (%) | 106 (30.2) | 226 (31.9) | .58 | 62 (32) | 73 (37.6) | .31 |
 30-day mortality (%) | 92 (26.2) | 198 (27.9) | .60 | 48 (24.7) | 67 (34.5) | .051 |
 60-day mortality (%) | 112 (31.9) | 235 (33.1) | .71 | 61 (31.4) | 74 (38.1) | .24 |
 90-day mortality (%) | 129 (36.8) | 255 (36) | .84 | 74 (38.1) | 77 (39.7) | .83 |