Table 1 Clinical characteristics of four patients with delayed cerebral thrombosis complicating pneumococcal meningitis
From: Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study
Characteristic | Patient 1 | Patient 2 | Patient 3 | Patient 4 |
|---|---|---|---|---|
Age (years) | 39 | 52 | 73 | 68 |
Gender | Male | Male | Male | Female |
Predisposing conditions | ||||
Otitis or sinusitis | Present | Absent | Present | Absent |
Immunocompromised | No | Yes | No | No |
Glasgow Coma Scale score | 11 | 11 | 11 | 13 |
Neck stiffness | Yes | Yes | Yes | Yes |
CSF leucocyte count (cells/mm3) | 1780 | 51 | 17,700 | 9 |
Time to secondary deterioration (days) | 14 | 10 | 7 | 6 |
Cranial imaging | MRI: infarction of the thalami, brain stem and cerebral hemispheres MRA: dilatation of the basilar artery | MRI: infarction of the brain stem, cerebellum, basal ganglia and temporal lobes | MRI: infarction in brainstem and cerebral hemispheres | MRI: infarction of the brain stem, thalamus and cerebral hemispheres MRA: convolution of basilar artery |
Time to death (days) | 32 | 12 | 25 | 16 |