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Table 2 Neuropathological findings of patients with pneumococcal meningitis

From: Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study

Type

Age yrs (M/F)

Days admission-autopsy

DXM

Parenchymal infiltration

Meningeal artery inflammation

Arterial thrombosis

Infarction

Area infarction

Bleeding

Area bleeding

Total pathology score

DCT 1

52, M

10

+

+++

+++

++

+++

Basal ganglia, cerebellum, brainstem

+

Focal minor

19

DCT 2

39, M

35

+

+

++

+++

Cortex, basal ganglia, cerebellum, brainstem

+

Focal minor

10

DCT 3

73, M

24

+

+

++

+++

+++

Cortex, cerebellum

+

Focal minor

17

DCT 4

68, F

15

+

+

+++

++

+++

Cortex, basal ganglia, cerebellum, brainstem

+

Focal minor

15

Control

46, M

7

_

++

+++

+++

++

Cortex, basal ganglia, brainstem

+++

Cortex, brainstem, cerebellum

22

Control

78, F

18

+

++

+++

+

+++

Cortex, basal ganglia, cerebellum, brainstem

+++

?

19

Control

73, F

21

+

++

++

++

++

Cortex, basal ganglia, brainstem

+

Brainstem, cerebellum

14

Control

48, F

30

+

++

+++

++

Cortex, basal ganglia, cerebellum, brainstem

+++

Basal ganglia

16

Control

88, F

30

?

++

++

+

Cortex, cerebellum, brainstem

++

Brainstem, cerebellum

15

Control

75, M

30

?

++

+++

++

+++

Cortex

+

?

19

Control

79, M

12

+

++

++

Cortex

14

Control

71, F

15

?

+

++

Cortex

+

?

6

  1. DCT delayed cerebral thrombosis, DXM dexamethasone