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Table 3 Factors associated with resolving AKI

From: Duration of acute kidney injury in critically ill patients

n = 236 Univariate Cox regression (hazard ratio) p value Multivariate Cox regression (hazard ratio) p value
HR (95% CI) HR (95% CI)
Age, per 10 year increase 0.94 0.86–1.03 0.19    
Female gender 0.85 0.61–1.17 0.31    
White race 1.03 0.70–1.51 0.88    
Hispanic or Latino ethnic group 1.50 0.98–2.30 0.06    
BMI 1.00 0.98–1.02 0.88    
Diabetes mellitus 0.91 0.61–1.34 0.63    
History of hypertension 0.91 0.65–1.26 0.55    
Platelet count    < 0.001    0.27
 > 150 × 109/L 1    1   
 < 150 × 109/L 0.54 0.38–0.78   0.80 0.53–1.19  
Urine output    < 0.0001    0.01
 > 0.5 mL/kg/h 1    1   
 < 0.5 mL/kg/h 0.31 0.20–0.47   0.53 0.32–0.87  
PaO2/FiO2 ratio    < 0.0001    0.001
 > 200 1    1   
 < 200 0.52 0.38–0.71   0.59 0.44–0.81  
Creatinine mg/dl, per unit increase 0.59 0.48–0.74 < 0.0001 0.71 0.57–0.89 0.003
Systolic BP, per 10 mm Hg increase 1.15 1.05–1.25 0.002 1.09 0.99–1.20 0.07
Vasopressor use 0.46 0.32–0.67 < 0.0001 0.91 0.59–1.41 0.68
  1. Factors associated with resolving AKI, defined as an AKI duration of less than 7 days, analyzed by the proportional subdistribution hazards model proposed by Fine and Gray, with death as a competing risk. Two patients were excluded from the original population (n = 238) due to missing values
  2. AKI acute kidney injury, BMI body mass index, BP blood pressure, PaO 2 /FiO 2 ratio partial pressure arterial oxygen/fraction of inspired oxygen