Table 1 Demographics and clinical data of patients with appropriate and non-appropriate procalcitonin (PCT) measurement series
Patients with appropriate PCT series (n = 42) | Patients with non-appropriate PCT series (n = 25) | p value | |
|---|---|---|---|
Age, years (median [IQR]) | 68 [59–76] | 76 [68–79] | 0.172 |
SAPS II score (median [IQR]) | 40 [29–51] | 38 [32–47] | 0.807 |
Male gender (% [95% CI]) | 59.5 [43.3–74.4] | 60.0 [38.7–78.9] | 0.999 |
ICU mortality (% [95% CI]) | 40.5 [26–57] | 32.0 [14.9–53.5] | 0.604 |
Ventilation hours (median [IQR]) | 423 [68–840] | 102 [8–335] | 0.012 |
ICU LOS, days (median [IQR]) | 17 [5–41] | 11 [4–21] | 0.264 |
Hospital LOS, days (median [IQR]) | 42 [25–73] | 39 [25–54] | 0.351 |
SOFA score max (median [IQR]) | 11 [9–13] | 9 [8–11] | 0.112 |
Length of antibiotic treatment, days (median [IQR]) | 10 [7–13] | 5 [4–6] | < 0.001 |
Antibiotic use density, DDD (median [IQR]) | 11 [9–23] | 6 [4–9] | < 0.001 |
Initial PCT value, ng/mL (median [IQR]) | 9.15 [3.1–32.4] | 1.55 [0.9–4.6] | 0.001 |
Peak PCT value, ng/mL (median [IQR]) | 30.2 [7.1–60.7] | 3.8 [1.6–10.3] | < 0.001 |
% [95% CI] (n) | % [95% CI] (n) | |
|---|---|---|
Cause of infection | ||
Abdominal sepsis | 52.4 [36.4–67.9] (22) | 44.0 [24.4–65.1] (11) |
Bloodstream infection | 0 | 4.0 [0.1–20.3] (1) |
Pleural empyema | 9.5 [2.6–22.6] (4) | 0 |
Pneumonia | 19.0 [8.6–34.1] (8) | 32.0 [14.9–53.5] (8) |
Prosthetic infection | 0 | 8.0 [1.0–26.0] (2) |
Urogenital sepsis | 9.5 [2.6–22.6] (4) | 8.0 [1.0–26.0] (2) |
Soft tissue infection | 2.4 [0.6–12.6] (1) | 4.0 [0.1–20.3] (1) |
Unknown | 7.1 [1–19] (3) | 0 |