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Table 2 Demographics and clinical data of patients with and without procalcitonin (PCT) stopping advice

From: Adherence to a procalcitonin-guided antibiotic treatment protocol in patients with severe sepsis and septic shock

  Patients with PCT stopping advice (n = 26) Patients without PCT stopping advice (n = 16) p value
Age, years (median [IQR]) 68 [59–75] 70 [62–79] 0.475
SAPS II score (median [IQR]) 40 [29–51] 44 [33–52] 0.597
Male gender (% [95% CI]) 69.2 [48.2–85.7] 43.8 [19.8–70.1] 0.121
ICU mortality (% [95% CI]) 26.9 [11.6–47.8] 62.5 [35.4–84.8] 0.029
Ventilation hours (median [IQR]) 597 [96–1260] 238 [47–461] 0.068
ICU LOS, days (median [IQR]) 23 [5–56] 11 [5–20] 0.212
Hospital LOS, days (median [IQR]) 56 [35–100] 23 [17–44] 0.002
SOFA score max (median [IQR]) 11 [9–12] 13 [9–15] 0.320
Length of antibiotic treatment, days (median [IQR]) 10 [8–13] 10 [7–12] 0.398
Antibiotic use density, DDD (median [IQR]) 13 [10–24] 10 [8–15] 0.136
Initial PCT value, ng/mL (median [IQR]) 20.0 [3.3–42.7] 5.1 [2.8–10.8] 0.136
Peak PCT value, ng/mL (median [IQR]) 40.5 [9.2–69.7] 16.2 [6.0–32.5] 0.095
  % [95% CI] (n) % [95% CI] (n)
Cause of infection
Abdominal sepsis 57.7 [36.9,76.6] (15) 43.8 [19.8–70.1] (7)
Bloodstream infection 0 0
Pleural empyema 11.5 [2.4–30.2] (3) 6.3 [0.2–30.2] (1)
Pneumonia 26.9 [11.5–47.8] (7) 6.3 [0.2–30.2] (1)
Prosthetic infection 0 0
Urogenital sepsis 3.8 [0.1–19.6] (1) 18.8 [4.0–45.6] (3)
Soft tissue infection 0 6.3 [0.2–30.2] (1)
Unknown 0 18.8 [4.0–45.6] (3)
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