Table 2 Demographics and clinical data of patients with and without procalcitonin (PCT) stopping advice
Patients with PCT stopping advice (n = 26) | Patients without PCT stopping advice (n = 16) | p value | |
|---|---|---|---|
Age, years (median [IQR]) | 68 [59–75] | 70 [62–79] | 0.475 |
SAPS II score (median [IQR]) | 40 [29–51] | 44 [33–52] | 0.597 |
Male gender (% [95% CI]) | 69.2 [48.2–85.7] | 43.8 [19.8–70.1] | 0.121 |
ICU mortality (% [95% CI]) | 26.9 [11.6–47.8] | 62.5 [35.4–84.8] | 0.029 |
Ventilation hours (median [IQR]) | 597 [96–1260] | 238 [47–461] | 0.068 |
ICU LOS, days (median [IQR]) | 23 [5–56] | 11 [5–20] | 0.212 |
Hospital LOS, days (median [IQR]) | 56 [35–100] | 23 [17–44] | 0.002 |
SOFA score max (median [IQR]) | 11 [9–12] | 13 [9–15] | 0.320 |
Length of antibiotic treatment, days (median [IQR]) | 10 [8–13] | 10 [7–12] | 0.398 |
Antibiotic use density, DDD (median [IQR]) | 13 [10–24] | 10 [8–15] | 0.136 |
Initial PCT value, ng/mL (median [IQR]) | 20.0 [3.3–42.7] | 5.1 [2.8–10.8] | 0.136 |
Peak PCT value, ng/mL (median [IQR]) | 40.5 [9.2–69.7] | 16.2 [6.0–32.5] | 0.095 |
% [95% CI] (n) | % [95% CI] (n) | |
|---|---|---|
Cause of infection | ||
Abdominal sepsis | 57.7 [36.9,76.6] (15) | 43.8 [19.8–70.1] (7) |
Bloodstream infection | 0 | 0 |
Pleural empyema | 11.5 [2.4–30.2] (3) | 6.3 [0.2–30.2] (1) |
Pneumonia | 26.9 [11.5–47.8] (7) | 6.3 [0.2–30.2] (1) |
Prosthetic infection | 0 | 0 |
Urogenital sepsis | 3.8 [0.1–19.6] (1) | 18.8 [4.0–45.6] (3) |
Soft tissue infection | 0 | 6.3 [0.2–30.2] (1) |
Unknown | 0 | 18.8 [4.0–45.6] (3) |