Table 3 Univariate analysis comparing laboratory findings in patients with Mycoplasma pneumoniae versus Streptococcus pneumoniae pneumonia
From: Severe atypical pneumonia in critically ill patients: a retrospective multicenter study
N (%) or median (IQR) | Total (N = 152) | Mycoplasma pneumoniae patients (N = 76) | Streptococcus pneumoniae patients (N = 76) | p value |
|---|---|---|---|---|
Laboratory features | ||||
Lactate (mmol/l) | 2.2 [1.6–3.3] | 1 [0.7–2.7] | 2.3 [1.8–3.4] | 0.003 |
P/F ratio | 163 [92–267] | 120 [88–236] | 178 [114–280] | 0.051 |
Serum sodium (mmol/L) | 136 [133–139] | 137 [135–140] | 136 [132–139] | 0.028 |
Creatinine (µmol/L) | 87 [65–139.5] | 77 [57.5–108] | 101 [69.5–168.8] | 0.008 |
CPK (IU/l) | 122 [40–309] | 138 [89–608] | 108 [36–202] | 0.093 |
ASAT (IU/l) | 38 [23–80] | 44 [24–81] | 38 [22–77] | 0.45 |
Bilirubin (µmol/l) | 12.8 [8–21.7] | 8.4 [5.8–13] | 15 [9.2–24.5] | 0.0006 |
Leukocytes | 11,400 [7200–16,300] | 11,140 [8100–17,000] | 11,200 [5112–16,142] | 0.63 |
Hemoglobin (g/dL) | 11.6 [10–12.9] | 11.3 [9.6–13.1] | 11.6 [10.2–12.8] | 0.89 |
Platelets (Giga/L) | 217 [138–287] | 262.5 [179.5–311.25] | 204 [138–252] | 0.009 |
Cytolysis | 21 (14%) | 8 (11%) | 13 (17%) | 0.35 |
Hemolytic anemia/cold agglutinins | 9 (6%) | 9 (12%) | 0 | 0.003 |
Rhabdomyolysis | 5 (3%) | 2 (3%) | 3 (4%) | 1 |
Radiological features | ||||
Number of quadrants involved | 0.013 | |||
≤ 2 | 103 (68%) | 37 (49%) | 66 (87%) | |
> 2 | 25 (16%) | 16 (21%) | 9 (12%) | |
Alveolar opacities | 111 (85%) | 42 (75%) | 19 (68%) | 0.013 |
Interstitial opacities | 26 (20%) | 20 (36%) | 12 (43%) | 0.0001 |
Pleural effusion | 20 (15%) | 3 (5%) | 3 (11%) | 0.007 |