When timing and dose of nutrition support were examined, the modified Nutrition Risk in Critically Ill (mNUTRIC) score did not differentiate high-risk patients who would derive the most benefit from nutrition support: a prospective cohort study

Lew, Charles Chin Han; Wong, Gabriel Jun Yung; Cheung, Ka Po; Fraser, Robert J. L.; Chua, Ai Ping; Chong, Mary Foong Fong; Miller, Michelle

doi:10.1186/s13613-018-0443-1

Annals of Intensive Care

Table 2 Comparison of the mode of feeding, source, goal, and achieved energy and protein intake between 28-day survivors and non-survivors stratified by days of exclusive nutrition support

From: When timing and dose of nutrition support were examined, the modified Nutrition Risk in Critically Ill (mNUTRIC) score did not differentiate high-risk patients who would derive the most benefit from nutrition support: a prospective cohort study

Nutrition parameters	Short-term exclusive nutrition support (≤ 6 days)			Longer-term exclusive nutrition support (≥ 7 days)
Nutrition parameters	Survivors (n = 62)	Non-survivors (n = 44)	p	Survivors (n = 106)	Non-survivors (n = 40)	p
Mode of feeding
Enteral	60 [96.8]	42 [95.5]	0.725	92 [86.8]	31 [77.5]	0.169
Parenteral	1 [1.6]	0 [0.0]	0.397	8 [7.5]	4 [10.0]	0.630
Combination	1 [1.6]	2 [4.5]	0.370	6 [5.7]	5 [12.5]	0.163
Energy
Goal (kcal/kg)	25.5 (5.5)	25.9 (6.3)	0.680	25.9 (4.4)	24.8 (4.3)	0.166
Actual intake (kcal/kg)	10.0 (6.0)	15.0 (6.4)	< 0.001	17.7 (5.2)	16.9 (5.7)	0.389
Actual intake (% goal/kg)	40.0 (22.4)	59.2 (24.1)	< 0.001	68.8 (17.8)	68.2 (19.5)	0.857
Energy sources (%)
Enteral	82.2 (24.9)	80.8 (28.7)	0.785	82.6 (29.5)	86.0 (23.3)	0.506
IV dextrose	6.7 (17.5)	11.4 (21.3)	0.215	1.4 (2.9)	1.5 (3.3)	0.769
Propofol	10.1 (14.7)	4.1 (6.2)	0.005	5.2 (6.5)	5.3 (9.4)	0.944
Parenteral	1.0 (7.8)	3.7 (17.2)	0.333	10.8 (29.4)	7.1 (21.8)	0.468
Protein
Goal (g/kg)	1.14 (0.20)	1.15 (0.26)	0.779	1.20 (0.21)	1.15 (0.26)	0.281
Actual intake (g/kg)	0.39 (0.26)	0.57 (0.30)	0.001	0.79 (0.24)	0.71 (0.28)	0.125
Actual intake (% goal/kg)	34.7 (21.6)	51.4 (26.4)	0.001	66.1 (18.9)	61.6 (19.4)	0.206
Protein sources (%)
Enteral	98.8 (9.6)	95.5 (20.8)	0.338	88.5 (31.2)	92.3 (23.7)	0.486
Parenteral	1.2 (9.6)	4.5 (20.8)	0.338	11.5 (31.2)	7.7 (23.7)	0.486
Per cent protein energy^a	14.6 (5.1)	15.1 (5.9)	0.600	17.9 (3.5)	16.8 (3.8)	0.100
Fed ≤ 48 h of ICU adm	59 [95.2]	43 [97.7]	0.495	101 [95.3]	37 [92.5]	0.510
Days on ENS	3.0 (3.0, 4.0)	3.0 (3.0, 5.0)	0.735	14.0 (12.0, 14.0)	14.0 (9.3, 14.0)	0.126
Blood glucose (mmol/L)^b	8.7 (2.9)	8.8 (2.3)	0.846	8.7 (2.3)	9.1 (2.3)	0.345
GRV > 200 mL^c	0.0 (0.0, 0.3)	0.3 (0.0, 0.7)	0.001	0.2 (0.0, 0.5)	0.0 (0.0, 0.3)	0.140
Hypoglycaemia^c,d	0.0 (0.0, 0.0)	0.0 (0.0, 0.3)	0.420	0.2 (0.0, 0.5)	0.0 (0.0, 0.3)	0.440

Values are mean (SD), median (q1, q3), or count [percentage]
adm, admission; ENS, exclusive nutrition support; GRV, gastric residual volume; ICU, intensive care unit; IV, intravenous; mNUTRIC, modified Nutrition Risk in Critically Ill score
^aPercentage of energy provided by protein relative to the total energy intake
^bAverage of daily measurements at 8 am on exclusive nutrition support
^cEpisodes per day on exclusive nutrition support
^dBlood glucose < 4.0 mmol/L

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