Validation of a new WIND classification compared to ICC classification for weaning outcome

Annals of Intensive Care

Table 4 Clinical outcomes of total cohort, excluded patients by ICC classification, and Group NW by WIND classification

Variables	Total (n = 1600)	ICC	WIND
Variables	Total (n = 1600)	Excluded (n = 865)	Group NW (n = 580)
Interval between intubation and the first SA, days^a	3 (2–6)	4 (2–10)	–
SOFA score at the day of first SA^a	5 (3–8)	7 (5–9)	–
MV days	5 (2–11)	6 (2–15)	5 (2–11)
Ventilator-free days^b	2 (0–24)	0 (0–0)	0
Tracheostomy	436 (27.3)	277 (32.0)	101 (17.4)
No	1164 (72.8)	568 (65.7)	479 (82.6)
Before MV	20 (1.3)	20 (2.3)	6 (1.0)
Between MV and first SA	219 (13.7)	219 (25.3)	95 (16.4)
Between first SA and extubation	151 (9.4)	54 (6.2)	–
After the first extubation	46 (2.9)	4 (0.5)	–
Interval between intubation and tracheostomy, days^c	11 (6–15)	9 (5–14)	10 (7–14)
Successful weaning from MV^d	824 (51.5)	160 (18.5)	0
ICU mortality	656 (41.0)	588 (68.0)	511 (88.1)
LOS in ICU, days	7 (4–15)	8 (3–17)	6 (2–13)
Hospital mortality	848 (53.0)	643 (74.3)	520 (89.7)
LOS in hospital, days	24 (13–46)	20 (9–43)	15 (5–30)
Type of discharge
Home	422 (26.4)	44 (5.1)	0
Other hospital	219 (13.7)	90 (10.4)	5 (0.9)
Other ICU	24 (1.5)	20 (2.3)	10 (1.7)
Hospice	87 (5.4)	68 (7.9)	45 (7.8)
Death	848 (53.0)	643 (74.3)	520 (89.7)

ICC International Consensus Conference, NW no weaning, WIND Weaning according to a New Definition, SA separation attempt, SOFA Sequential Organ Failure Assessment, MV mechanical ventilation, ICU intensive care unit, LOS length of stay
^aExcluded patients who had no SA from MV. Therefore, total patients, excluded patients by ICC, and Group NW by WIND numbered 1020, 285, and 0, respectively
^bVentilator-free days are defined as 28 minus the total number of days with invasive MV. Nonsurvivors were considered as having 0 ventilator-free days
^cExcluded patients with no tracheostomy or tracheostomy prior to mechanical ventilation
^dSuccessful weaning is defined as in the WIND Study (Intubated patients: extubation without death or reintubation within 7 days after extubation [whether postextubation noninvasive ventilation was used or not] or ICU discharge without invasive mechanical ventilation within 7 days, whichever comes first. Tracheostomized patients: spontaneous ventilation through tracheostomy without any mechanical ventilation during 7 consecutive days or ICU discharge with spontaneous breathing, whichever comes first)