Table 4 Biological results
Patients in hemoperfusion group/control group | Day 1 (n = 18) 9/9 | Day 2 (posttreatment) (n = 16) 9/7 | Day 3 (n = 15) 9/6 | Day 4 (n = 15) 9/6 | Day 5 (n = 15) 9/6 |
|---|---|---|---|---|---|
Lactate (mg/dl), mean (SD) | |||||
Hemoperfusion group | 56.7 (33) | 41.3 (32.7) | 35.2 (34) | 26.6 (10.4) | 21.3 (14.2) |
Control group | 56.4 (26.7) | 37.7 (26.3) | 19.8 (7.5) | 17 (3.8) | 17 (3.8) |
CRP (mg/dl), mean (SD) | |||||
Hemoperfusion group | 33.5 (10.7) | 30.4 (14.9) | 27.6 (19.5) | 16.8 (9.7) | 14.1 (7.8) |
Control group | 24.6 (10.3) | 24.1 (10.3) | 12.9 (5) | 8.2 (5.7) | 7.4 (9.3) |
PCT (ng/ml), mean (SD) | |||||
Hemoperfusion group | 83 (92) | 43 (59) | 33.2 (45.8) | 19.9 (27.2) | 17.7 (23) |
Control group | 71 (67) | 40 (24) | 27.9 (21.2) | 12.7 (12.4) | 6.1 (5.4) |
Adren (nmol/l), mean (SD) | |||||
Hemoperfusion group | 17.8 (4.8) | 10.9 (3.7) | 7.2 (2.4) | 5.6 (2.1) | 6.4 (1.8) |
Control group | 17.7 (5.8) | 12.3 (3.3) | 6.7 (1.8) | 4.1 (2) | 4.8 (3.6) |
IL-6 (ng/ml), mean (SD) | |||||
Hemoperfusion group | 1115 (777) | 387 (548) | 317 (400) | 94.5 (120) | 367.8 (577) |
Control group | 8302 (6830)* | 3698 (6285) | 634 (1292) | 9.8 (4.3) | 19.2 (14.2) |
IL-8 (pg/ml), mean (SD) | |||||
Hemoperfusion group | 566.8 (291) | 271 (278) | 144 (88) | 141 (118) | 150 (126) |
Control group | 2766 (3684) | 1412 (3090) | 781 (1254) | 29.4 (8.6) | 40.6 (57) |
IL-10 (pg/ml), mean (SD) | |||||
Hemoperfusion group | 427.1 (339) | 178.5 (122) | 283.8 (287) | 162.7 (164) | 131.7 (198) |
Control group | 3411 (8650) | 335 (361) | 231 (323) | 54.4 (47.4) | 77 (95) |
IL-1β (pg/ml), mean (SD) | |||||
Hemoperfusion group | 4.7 (1.8) | 3.7 (0.93) | 3.6 (0.6) | 3.4 (0.4) | 5.3 (3) |
Control group | 35.1 (90) | 2.1 (1.5) | 89 (195) | 2.4 (1.5) | 1.8 (1.5) |
TNFα (pg/ml), mean (SD) | |||||
Hemoperfusion group | 177.2 (111) | 56.8 (26.7) | 78.2 (108) | 47.7 (36.5) | 49.1 (51) |
Control group | 386 (493) | 76.6 (72.8) | 170 (355) | 28.7 (20.7) | 27.4 (8) |
SuPAR (ng/ml), mean (SD) | |||||
Hemoperfusion group | 23.1 (9.8) | 24.5 (12) | 24.9 (17.5) | 21.8 (13.3) | 16.1 (6.8) |
Control group | 34.2 (21.2) | 24.8 (9.4) | 23.8 (15.3) | 18.2 (11.5) | 15.3 (5.4) |
NGAL (ng/ml), mean (SD) | |||||
Hemoperfusion group | 2331 (1028) | 1725.2 (645) | 1261 (382) | 987 (346) | 749 (197) |
Control group | 2264 (1444) | 1284 (1037) | 783 (671) | 574 (593) | 600 (674) |