Table 1 Study population characteristics and last ventilator settings prior to high-frequency oscillatory ventilation
Variable | No or mild PARDS (N = 62) | Moderate PARDS (N = 29) | Severe PARDS (N = 24) |
|---|---|---|---|
Age (months) | 4.5 (2.0–12.5) | 5.0 (2.0–24.5) | 6.0 (1.8–20.23) |
 0–12 months (%) | 75.8 | 69.0 | 66.7 |
 13–60 months (%) | 14.5 | 20.7 | 20.8 |
 > 60 months (%) | 9.7 | 10.3 | 12.5 |
Male (%) | 54.8 | 48.3 | 45.8 |
Weight (kg) | 7.0 (4.5–10.8) | 5.5 (3.8–11.5) | 6.9 (4.1–11.3) |
PRISM-III 24 h* | 6.0 (3.0–8.0) | 6.0 (3.0–6.5) | 12.5 (8.23–37.78) |
Admission diagnosis (%) | Â | Â | Â |
 Pulmonary | 85.5 | 79.3 | 79.2 |
 PHT | 1.6 | 0 | 8.3 |
 Acute liver failure | 0 | 0 | 8.3 |
 Pancreatitis | 1.6 | 0 | 0 |
 Sepsis | 9.7 | 13.8 | 4.2 |
 Post-operative | 1.6 | 6.9 | 0 |
PICU stay (days) | 10.0 (7–17) | 10.0 (8.0–15.0) | 12.5 (8.3–37.8) |
PICU mortality (%)* | 6.5 | 10.3 | 33.3 |
Last ventilator settings on conventional mechanical ventilation before switch to HFOV | |||
PIP (cmH2O) | 29 (27–32) | 28 (26–30) | 29 (27–33) |
mPaw (cmH2O) | 15 (14–16) | 16 (14–17) | 17 (15–19) |
PEEP (cmH2O) | 7.0 (6.0–8.1) | 7.8 (6.5–8.1) | 7.4 (6.7–9.9) |
Vtexp (mL/kg) | 6.3 (5.7–7.5) | 7.0 (6.3–7.9) | 7.0 (6.2–8.0) |
FiO2* | 0.61 (0.50–0.99) | 0.75 (0.55–0.90) | 0.99 (0.75–1.0) |
 Time on CMV before start HFOV (h) | 10 (3–14) | 10 (5–17) | 11 (3–16) |
 Total length of HFOV run (h) | 91 (66–123) | 102 (67–149) | 134 (69–224) |
 Total length of CMV run after HFOV (h) | 72 (28–160) | 73 (12–169) | 77 (22–172) |