Table 1 Comparison of baseline characteristics between elderly and very elderly patients
Elderly (n = 1193) (80.1%) | Very elderly (n = 297) (19.9%) | Overall (n = 1490) | p | |
|---|---|---|---|---|
Age (years) mean (SD) | 72.4 (4.1) | 82.8 (2.7) | 74.5 (5.6) | < 0.001 Ç |
APACHE II modified score mean (SD) | 17.2 (7.0) | 16.7 (7.2) | 17.1 (7.0) | 0.374 Ç |
Number of organs involved on admission mean (SD) | 2.9 (1.4) | 2.9 (1.4) | 2.9 (1.4) | 0.888 Ç |
ICU LOS mean (SD) | 14.5 (18.8) | 11.5 (20.4) | 13.9 (19.2) | 0.014 Ç |
Median | 7.7 | 5.4 | 7.2 | 0.012 |
Median in survivors | 7.8 | 7.5 | 7.4 | 0.7 |
Median in nonsurvivors | 5.8 | 5.3 | 7.8 | 0.5 |
Mortality N (%)* | 727 (48.8) | 161 (54.2) | 727 (48.8) | 0.027* |
Sex (male) N (%)* | 719 (60.3) | 157 (52.9) | 876 (58.8) | 0.020* |
Admission category N (%) | ||||
Medical | 715 (60.2) | 138 (46.6) | 853 (57.2) | < 0.001* |
Urgent surgery | 361(30.4) | 146 (49.3) | 507 (34.0) | |
Elective surgery | 97 (8.2) | 10 (3.4) | 107 (7.2) | |
Trauma | 14 (1.2) | 2 (0.7) | 16 (1.1) | |
Source of infection N (%) | ||||
Pneumonia | 391 (32.8) | 68 (22.9) | 459 (30.8) | < 0.001* |
Peritonitis | 396 (33.2) | 135 (45.5) | 531 (35.6) | |
UTI | 137 (11.5) | 38 (12.8) | 175 (11.7) | |
SSTI | 56 (4.7) | 10 (3.4) | 66 (4.4) | |
Catheter-related bacteraemia | 30 (2.5) | 2 (0.7) | 32 (2.1) | |
Other | 147 (12.3) | 39 (13.1) | 186 (12.5) | |
Patient location at sepsis diagnosis N (%) | ||||
ED | 469 (39.3) | 127 (42.8) | 596 (40.0) | 0.023* |
Ward | 547 (45.9) | 144 (48.5) | 691 (46.4) | |
ICU | 177 (14.8) | 26 (8.8) | 203 (13.6) | |
Baseline acute organ dysfunction N (%) | ||||
Cardiovascular | 1023 (85.8) | 245 (82.5) | 1268(85.1) | 0.158* |
Pulmonary | 250 (21.0) | 62 (20.9) | 312 (20.9) | 0.976* |
Renal | 940 (78.8) | 241 (81.1) | 1181(79.3) | 0.371* |
Hepatic | 191 (16.0) | 50 (16.8) | 241 (16.2) | 0.730* |
Thrombocytopenia | 263 (22.0) | 60 (20.2) | 323 (21.7) | 0.490* |
Coagulopathy | 415 (34.8) | 104 (35.0) | 519 (34.8) | 0.941* |
Sepsis resuscitation bundle N (%)$ | 102 (8.5) | 14 (4.7) | 116 (7.8) | 0.027* |
Sepsis management bundle N (%)$ | 165 (13.8) | 32 (10.8) | 197 (13.2) | 0.164* |